Progress and application of functional magnetic resonance imaging in acute kidney injury
Acute kidney injury （AKI） is a globally highly prevalent clinical syndrome characterized by a sudden deterioration of renal function. It occurs in a variety of clinical conditions and its severity is closely associated with increased subsequent mortality， poor prognosis， and chronicity of renal inju...
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Editorial Department of Journal of Clinical Nephrology
2025-03-01
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| Series: | Linchuang shenzangbing zazhi |
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| Online Access: | http://www.lcszb.com/article/doi/10.3969/j.issn.1671-2390.2025.03.010 |
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| author | Liu Zi-yang Luo Jing Jiang Lei Cao Hong-di |
| author_facet | Liu Zi-yang Luo Jing Jiang Lei Cao Hong-di |
| author_sort | Liu Zi-yang |
| collection | DOAJ |
| description | Acute kidney injury （AKI） is a globally highly prevalent clinical syndrome characterized by a sudden deterioration of renal function. It occurs in a variety of clinical conditions and its severity is closely associated with increased subsequent mortality， poor prognosis， and chronicity of renal injury. Therefore， an early recognition of AKI and timely interventions are crucial. Currently， there are limited clinical diagnostic techniques for AKI， and there lacks sufficiently sensitive and widely available monitoring methods. Functional magnetic resonance imaging （fMRI） is an increasingly powerful imaging modality， including blood oxygenation level dependent （BOLD）， arterial spin labeling （ASL）， diffusion weighted imaging （DWI）， intravoxel incoherent motion （IVIM）， diffusion kurtosis imaging （DKI）， diffusion tensor imaging （DTI）， and T1 mapping， T2 mapping， etc. These techniques can non-invasively assess renal oxygenation and perfusion， and reflect the changes in renal microstructure， providing the potential to detect AKI and predict the long-term outcome of AKI. This review summarized the recent studies of fMRI in AKI and provides a reference for future clinical applications. |
| format | Article |
| id | doaj-art-c19288401f7f4421aeb7054eea98df2f |
| institution | DOAJ |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2025-03-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-c19288401f7f4421aeb7054eea98df2f2025-08-20T02:40:50ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902025-03-0125324224810.3969/j.issn.1671-2390.2025.03.0101671-2390（2025）03-0242-07Progress and application of functional magnetic resonance imaging in acute kidney injuryLiu Zi-yang0Luo Jing1Jiang Lei2Cao Hong-di3Center for Kidney Disease， the Second Affiliated Hospital of Nanjing Medical University， Nanjing 210003， ChinaCenter for Kidney Disease， the Second Affiliated Hospital of Nanjing Medical University， Nanjing 210003， ChinaCenter for Kidney Disease， the Second Affiliated Hospital of Nanjing Medical University， Nanjing 210003， ChinaCenter for Kidney Disease， the Second Affiliated Hospital of Nanjing Medical University， Nanjing 210003， ChinaAcute kidney injury （AKI） is a globally highly prevalent clinical syndrome characterized by a sudden deterioration of renal function. It occurs in a variety of clinical conditions and its severity is closely associated with increased subsequent mortality， poor prognosis， and chronicity of renal injury. Therefore， an early recognition of AKI and timely interventions are crucial. Currently， there are limited clinical diagnostic techniques for AKI， and there lacks sufficiently sensitive and widely available monitoring methods. Functional magnetic resonance imaging （fMRI） is an increasingly powerful imaging modality， including blood oxygenation level dependent （BOLD）， arterial spin labeling （ASL）， diffusion weighted imaging （DWI）， intravoxel incoherent motion （IVIM）， diffusion kurtosis imaging （DKI）， diffusion tensor imaging （DTI）， and T1 mapping， T2 mapping， etc. These techniques can non-invasively assess renal oxygenation and perfusion， and reflect the changes in renal microstructure， providing the potential to detect AKI and predict the long-term outcome of AKI. This review summarized the recent studies of fMRI in AKI and provides a reference for future clinical applications.http://www.lcszb.com/article/doi/10.3969/j.issn.1671-2390.2025.03.010acute kidney injuryfunctional magnetic resonance imagingblood oxygenation level dependentintravoxel incoherent motionarterial spin labeling |
| spellingShingle | Liu Zi-yang Luo Jing Jiang Lei Cao Hong-di Progress and application of functional magnetic resonance imaging in acute kidney injury Linchuang shenzangbing zazhi acute kidney injury functional magnetic resonance imaging blood oxygenation level dependent intravoxel incoherent motion arterial spin labeling |
| title | Progress and application of functional magnetic resonance imaging in acute kidney injury |
| title_full | Progress and application of functional magnetic resonance imaging in acute kidney injury |
| title_fullStr | Progress and application of functional magnetic resonance imaging in acute kidney injury |
| title_full_unstemmed | Progress and application of functional magnetic resonance imaging in acute kidney injury |
| title_short | Progress and application of functional magnetic resonance imaging in acute kidney injury |
| title_sort | progress and application of functional magnetic resonance imaging in acute kidney injury |
| topic | acute kidney injury functional magnetic resonance imaging blood oxygenation level dependent intravoxel incoherent motion arterial spin labeling |
| url | http://www.lcszb.com/article/doi/10.3969/j.issn.1671-2390.2025.03.010 |
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