Reversal Rate of Clustering of Cardiovascular Disease Risk Factors of Metabolic Syndrome in the General Population: The Niigata Preventive Medicine Study
The reversal rate from clustering of cardiovascular disease (CVD) risk factors—components of the metabolic syndrome (MetS) is not known. Methods and Results. Among 35,534 subjects who received the annual health examinations at the NiigataHealth Foundation (Niigata, Japan), 4,911 subjects had cluster...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Journal of Obesity |
| Online Access: | http://dx.doi.org/10.1155/2010/623593 |
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| _version_ | 1849684305918296064 |
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| author | Shinsuke Okada Akiko Suzuki Hiroshi Watanabe Toru Watanabe Yoshifusa Aizawa |
| author_facet | Shinsuke Okada Akiko Suzuki Hiroshi Watanabe Toru Watanabe Yoshifusa Aizawa |
| author_sort | Shinsuke Okada |
| collection | DOAJ |
| description | The reversal rate from clustering of cardiovascular disease (CVD) risk factors—components of the metabolic syndrome (MetS) is not known. Methods and Results. Among 35,534 subjects who received the annual health examinations at the NiigataHealth Foundation (Niigata, Japan), 4,911 subjects had clustering of 3 or more of the following CVD risk factors: (1) body mass index (BMI) ≥25 Kg/m2, (2) blood pressure ≥130 mm Hg in systolic and/or ≥85 mm Hg in diastolic, (3) triglycerides ≥150 mg/dL, (4) high-density lipoprotein cholesterol ≤40 mg/dL in men, ≤50 mg/dL in women, and (5) fasting blood glucose ≥100 mg/dL. After 5 years 1,929 subjects had a reversal of clustering (39.4%). A reversal occurred more often in males. The subjects with a reversal of clustering had milder level of each risk factor and a smaller number of risk factors, while BMI was associated with the least chance of a reversal. Conclusion. We concluded that a reversal of clustering CVD risk factors is possible in 4/10 subjects over a 5-year period by habitual or medical interventions. Gender and each CVD risk factor affected the reversal rate adversely, and BMI was associated with the least chance of a reversal. |
| format | Article |
| id | doaj-art-c190bf99346543859671bb9767dadfba |
| institution | DOAJ |
| issn | 2090-0708 2090-0716 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Obesity |
| spelling | doaj-art-c190bf99346543859671bb9767dadfba2025-08-20T03:23:30ZengWileyJournal of Obesity2090-07082090-07162010-01-01201010.1155/2010/623593623593Reversal Rate of Clustering of Cardiovascular Disease Risk Factors of Metabolic Syndrome in the General Population: The Niigata Preventive Medicine StudyShinsuke Okada0Akiko Suzuki1Hiroshi Watanabe2Toru Watanabe3Yoshifusa Aizawa4Divisions of Endocrinology and Metabolism and Cardiology, Graduate School of Medical and Dental Science, Niigata University, Niigata 951-8510, JapanDivisions of Endocrinology and Metabolism and Cardiology, Graduate School of Medical and Dental Science, Niigata University, Niigata 951-8510, JapanDivisions of Endocrinology and Metabolism and Cardiology, Graduate School of Medical and Dental Science, Niigata University, Niigata 951-8510, JapanNiigata Health Foundation, Niigata 951-8581, JapanDivisions of Endocrinology and Metabolism and Cardiology, Graduate School of Medical and Dental Science, Niigata University, Niigata 951-8510, JapanThe reversal rate from clustering of cardiovascular disease (CVD) risk factors—components of the metabolic syndrome (MetS) is not known. Methods and Results. Among 35,534 subjects who received the annual health examinations at the NiigataHealth Foundation (Niigata, Japan), 4,911 subjects had clustering of 3 or more of the following CVD risk factors: (1) body mass index (BMI) ≥25 Kg/m2, (2) blood pressure ≥130 mm Hg in systolic and/or ≥85 mm Hg in diastolic, (3) triglycerides ≥150 mg/dL, (4) high-density lipoprotein cholesterol ≤40 mg/dL in men, ≤50 mg/dL in women, and (5) fasting blood glucose ≥100 mg/dL. After 5 years 1,929 subjects had a reversal of clustering (39.4%). A reversal occurred more often in males. The subjects with a reversal of clustering had milder level of each risk factor and a smaller number of risk factors, while BMI was associated with the least chance of a reversal. Conclusion. We concluded that a reversal of clustering CVD risk factors is possible in 4/10 subjects over a 5-year period by habitual or medical interventions. Gender and each CVD risk factor affected the reversal rate adversely, and BMI was associated with the least chance of a reversal.http://dx.doi.org/10.1155/2010/623593 |
| spellingShingle | Shinsuke Okada Akiko Suzuki Hiroshi Watanabe Toru Watanabe Yoshifusa Aizawa Reversal Rate of Clustering of Cardiovascular Disease Risk Factors of Metabolic Syndrome in the General Population: The Niigata Preventive Medicine Study Journal of Obesity |
| title | Reversal Rate of Clustering of Cardiovascular Disease Risk Factors of Metabolic Syndrome in the General Population: The Niigata Preventive Medicine Study |
| title_full | Reversal Rate of Clustering of Cardiovascular Disease Risk Factors of Metabolic Syndrome in the General Population: The Niigata Preventive Medicine Study |
| title_fullStr | Reversal Rate of Clustering of Cardiovascular Disease Risk Factors of Metabolic Syndrome in the General Population: The Niigata Preventive Medicine Study |
| title_full_unstemmed | Reversal Rate of Clustering of Cardiovascular Disease Risk Factors of Metabolic Syndrome in the General Population: The Niigata Preventive Medicine Study |
| title_short | Reversal Rate of Clustering of Cardiovascular Disease Risk Factors of Metabolic Syndrome in the General Population: The Niigata Preventive Medicine Study |
| title_sort | reversal rate of clustering of cardiovascular disease risk factors of metabolic syndrome in the general population the niigata preventive medicine study |
| url | http://dx.doi.org/10.1155/2010/623593 |
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