Microstructure Abnormalities of Diffusion Tensor Imaging Measures in First‐Episode, Treatment‐Naïve Adolescents With Major Depressive Disorder: An Integrated AFQ and TBSS Study

Microstructure Abnormalities of Diffusion Tensor Imaging Measures in First‐Episode, Treatment‐Naïve Adolescents With Major Depressive Disorder: An Integrated AFQ and TBSS Study

ABSTRACT Purpose Structural changes during depressive episodes in adolescents with major depressive disorder (MDD) remains unclear due to participant heterogeneity, illness chronicity, and medication confounders. This study aimed to explore white matter (WM) microstructural changes in first‐episode,...

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Main Authors: Wenjie Zhang, Chan Zhang, Jinyuan Zhao, Jiajing Cui, Jinji Bai, Xuan Deng, Junjun Ji, Ting Li, Yu Wang, Kefeng Li, Yunhui Qu, Junfeng Li
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Brain and Behavior
Subjects:
adolescents
automated fiber quantification
diffusion tensor imaging
major depressive disorder
tract‐based spatial statistics
Online Access:https://doi.org/10.1002/brb3.70416
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