Hubungan Nilai Treshold dengan KadarAngiotensin Converting Enzyme-2

Introduction: The coronavirus disease-19 (COVID-19) pandemic has been a major problem in every country worldwide. Cases of  COVID-19 in children are usually caused by exposure to infected family members or other adults infected with the disease. Clinical manifestations in children vary widely from s...

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Main Authors: Sabar Hutabarat, Eti Yerizel, Aisyah Elliyanti, Yulia Iriani
Format: Article
Language:English
Published: Universitas Andalas 2023-04-01
Series:Majalah Kedokteran Andalas
Online Access:https://jurnalmka.fk.unand.ac.id/index.php/art/article/view/1297
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author Sabar Hutabarat
Eti Yerizel
Aisyah Elliyanti
Yulia Iriani
author_facet Sabar Hutabarat
Eti Yerizel
Aisyah Elliyanti
Yulia Iriani
author_sort Sabar Hutabarat
collection DOAJ
description Introduction: The coronavirus disease-19 (COVID-19) pandemic has been a major problem in every country worldwide. Cases of  COVID-19 in children are usually caused by exposure to infected family members or other adults infected with the disease. Clinical manifestations in children vary widely from symptomatic to asymptomatic. This study aims to determine the relationship between cycle threshold (Ct) value with Angiotensin Converting Enzyme-2 (ACE-2)   Method: This study is an observational study with a cross-sectional design. The purpose is to analyze the relationship between Ct value with ACE-2, IL-6, IL-10 level in asymptomatic COVID-19 pediatric patients. Ct value measured using RT-PCR and ACE 2,  Il-6 and IL-10 were measured using ELISA examinations.   Result: Mean of ACE-2 is 132,66 ± 38,19 pg/mL (21,63 – 171,63 pg/m).   Conclusion: The majority of Ct value in asymptomatic pediatric COVID-19 patients were high (85,7%). Statistically, there was no significant correlation between Ct value with ACE-2, IL-6 and IL-10 in COVID-19 asymptomatic children.   Keyword: Angiotensin Converting Enzyme-2, Covid-19 Asymptomatic Children
format Article
id doaj-art-c1900bcd707a4a65a846cb38e6e52a71
institution OA Journals
issn 0126-2092
2442-5230
language English
publishDate 2023-04-01
publisher Universitas Andalas
record_format Article
series Majalah Kedokteran Andalas
spelling doaj-art-c1900bcd707a4a65a846cb38e6e52a712025-08-20T02:13:53ZengUniversitas AndalasMajalah Kedokteran Andalas0126-20922442-52302023-04-0146242442810.25077/mka.v46.i2.p424-428.2023734Hubungan Nilai Treshold dengan KadarAngiotensin Converting Enzyme-2Sabar HutabaratEti YerizelAisyah ElliyantiYulia IrianiIntroduction: The coronavirus disease-19 (COVID-19) pandemic has been a major problem in every country worldwide. Cases of  COVID-19 in children are usually caused by exposure to infected family members or other adults infected with the disease. Clinical manifestations in children vary widely from symptomatic to asymptomatic. This study aims to determine the relationship between cycle threshold (Ct) value with Angiotensin Converting Enzyme-2 (ACE-2)   Method: This study is an observational study with a cross-sectional design. The purpose is to analyze the relationship between Ct value with ACE-2, IL-6, IL-10 level in asymptomatic COVID-19 pediatric patients. Ct value measured using RT-PCR and ACE 2,  Il-6 and IL-10 were measured using ELISA examinations.   Result: Mean of ACE-2 is 132,66 ± 38,19 pg/mL (21,63 – 171,63 pg/m).   Conclusion: The majority of Ct value in asymptomatic pediatric COVID-19 patients were high (85,7%). Statistically, there was no significant correlation between Ct value with ACE-2, IL-6 and IL-10 in COVID-19 asymptomatic children.   Keyword: Angiotensin Converting Enzyme-2, Covid-19 Asymptomatic Childrenhttps://jurnalmka.fk.unand.ac.id/index.php/art/article/view/1297
spellingShingle Sabar Hutabarat
Eti Yerizel
Aisyah Elliyanti
Yulia Iriani
Hubungan Nilai Treshold dengan KadarAngiotensin Converting Enzyme-2
Majalah Kedokteran Andalas
title Hubungan Nilai Treshold dengan KadarAngiotensin Converting Enzyme-2
title_full Hubungan Nilai Treshold dengan KadarAngiotensin Converting Enzyme-2
title_fullStr Hubungan Nilai Treshold dengan KadarAngiotensin Converting Enzyme-2
title_full_unstemmed Hubungan Nilai Treshold dengan KadarAngiotensin Converting Enzyme-2
title_short Hubungan Nilai Treshold dengan KadarAngiotensin Converting Enzyme-2
title_sort hubungan nilai treshold dengan kadarangiotensin converting enzyme 2
url https://jurnalmka.fk.unand.ac.id/index.php/art/article/view/1297
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AT etiyerizel hubungannilaitresholddengankadarangiotensinconvertingenzyme2
AT aisyahelliyanti hubungannilaitresholddengankadarangiotensinconvertingenzyme2
AT yuliairiani hubungannilaitresholddengankadarangiotensinconvertingenzyme2