A Prospective Randomized Comparison of Postoperative Pain and Complications after Thyroidectomy under Different Anesthetic Techniques: Volatile Anesthesia versus Total Intravenous Anesthesia
While the postoperative outcome is favorable, post-thyroidectomy pain is considerable. Reducing the postoperative acute pain, therefore, is considered important. This study investigated whether the pain intensity and need for rescue analgesics during the immediate postoperative period after thyroide...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
|
| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2021/8876906 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832550516555513856 |
|---|---|
| author | Jun-Young Jo Yeon Ju Kim Seong-Soo Choi Jihoon Park Han Park Kyung-Don Hahm |
| author_facet | Jun-Young Jo Yeon Ju Kim Seong-Soo Choi Jihoon Park Han Park Kyung-Don Hahm |
| author_sort | Jun-Young Jo |
| collection | DOAJ |
| description | While the postoperative outcome is favorable, post-thyroidectomy pain is considerable. Reducing the postoperative acute pain, therefore, is considered important. This study investigated whether the pain intensity and need for rescue analgesics during the immediate postoperative period after thyroidectomy differ according to the methods of anesthesia. Seventy-two patients undergoing total thyroidectomy under general anesthesia were examined. Patients were randomly assigned to undergo either total intravenous anesthesia with remifentanil and propofol (TIVA, n = 35) or propofol induction and maintenance with desflurane and nitrous oxide (volatile anesthesia [VA], n = 37). The mean administered dose of remifentanil was 1977.7 ± 722.5 μg in the TIVA group, which was approximately 0.268 ± 0.118 μg/min/kg during surgery. Pain scores based on a numeric rating scale (NRS) and the need for rescue analgesics were compared between groups at the postoperative anesthetic care unit (PACU). The immediate postoperative NRS values of the TIVA and VA groups were 5.7 ± 1.7 and 4.7 ± 2.3, respectively (P = 0.034). Postoperative morphine equianalgesic doses in the PACU were higher in the TIVA group than in the VA group (16.7 ± 3.8 mg vs. 14.1 ± 5.9 mg, P = 0.027). The incidence of immediate postanesthetic complications did not differ significantly between groups. In conclusion, more rescue analgesics were required in the TIVA group than in the VA group to adequately manage postoperative pain while staying in the PACU after thyroidectomy. |
| format | Article |
| id | doaj-art-c184c7f746954e16bb92665fc6abf720 |
| institution | Kabale University |
| issn | 1203-6765 1918-1523 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-c184c7f746954e16bb92665fc6abf7202025-02-03T06:06:39ZengWileyPain Research and Management1203-67651918-15232021-01-01202110.1155/2021/88769068876906A Prospective Randomized Comparison of Postoperative Pain and Complications after Thyroidectomy under Different Anesthetic Techniques: Volatile Anesthesia versus Total Intravenous AnesthesiaJun-Young Jo0Yeon Ju Kim1Seong-Soo Choi2Jihoon Park3Han Park4Kyung-Don Hahm5Department of Anesthesiology and Pain Medicine, Laboratory for Perioperative Outcome Research, Asan Medical Centre, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Laboratory for Perioperative Outcome Research, Asan Medical Centre, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Laboratory for Perioperative Outcome Research, Asan Medical Centre, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Laboratory for Perioperative Outcome Research, Asan Medical Centre, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Laboratory for Perioperative Outcome Research, Asan Medical Centre, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Laboratory for Perioperative Outcome Research, Asan Medical Centre, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of KoreaWhile the postoperative outcome is favorable, post-thyroidectomy pain is considerable. Reducing the postoperative acute pain, therefore, is considered important. This study investigated whether the pain intensity and need for rescue analgesics during the immediate postoperative period after thyroidectomy differ according to the methods of anesthesia. Seventy-two patients undergoing total thyroidectomy under general anesthesia were examined. Patients were randomly assigned to undergo either total intravenous anesthesia with remifentanil and propofol (TIVA, n = 35) or propofol induction and maintenance with desflurane and nitrous oxide (volatile anesthesia [VA], n = 37). The mean administered dose of remifentanil was 1977.7 ± 722.5 μg in the TIVA group, which was approximately 0.268 ± 0.118 μg/min/kg during surgery. Pain scores based on a numeric rating scale (NRS) and the need for rescue analgesics were compared between groups at the postoperative anesthetic care unit (PACU). The immediate postoperative NRS values of the TIVA and VA groups were 5.7 ± 1.7 and 4.7 ± 2.3, respectively (P = 0.034). Postoperative morphine equianalgesic doses in the PACU were higher in the TIVA group than in the VA group (16.7 ± 3.8 mg vs. 14.1 ± 5.9 mg, P = 0.027). The incidence of immediate postanesthetic complications did not differ significantly between groups. In conclusion, more rescue analgesics were required in the TIVA group than in the VA group to adequately manage postoperative pain while staying in the PACU after thyroidectomy.http://dx.doi.org/10.1155/2021/8876906 |
| spellingShingle | Jun-Young Jo Yeon Ju Kim Seong-Soo Choi Jihoon Park Han Park Kyung-Don Hahm A Prospective Randomized Comparison of Postoperative Pain and Complications after Thyroidectomy under Different Anesthetic Techniques: Volatile Anesthesia versus Total Intravenous Anesthesia Pain Research and Management |
| title | A Prospective Randomized Comparison of Postoperative Pain and Complications after Thyroidectomy under Different Anesthetic Techniques: Volatile Anesthesia versus Total Intravenous Anesthesia |
| title_full | A Prospective Randomized Comparison of Postoperative Pain and Complications after Thyroidectomy under Different Anesthetic Techniques: Volatile Anesthesia versus Total Intravenous Anesthesia |
| title_fullStr | A Prospective Randomized Comparison of Postoperative Pain and Complications after Thyroidectomy under Different Anesthetic Techniques: Volatile Anesthesia versus Total Intravenous Anesthesia |
| title_full_unstemmed | A Prospective Randomized Comparison of Postoperative Pain and Complications after Thyroidectomy under Different Anesthetic Techniques: Volatile Anesthesia versus Total Intravenous Anesthesia |
| title_short | A Prospective Randomized Comparison of Postoperative Pain and Complications after Thyroidectomy under Different Anesthetic Techniques: Volatile Anesthesia versus Total Intravenous Anesthesia |
| title_sort | prospective randomized comparison of postoperative pain and complications after thyroidectomy under different anesthetic techniques volatile anesthesia versus total intravenous anesthesia |
| url | http://dx.doi.org/10.1155/2021/8876906 |
| work_keys_str_mv | AT junyoungjo aprospectiverandomizedcomparisonofpostoperativepainandcomplicationsafterthyroidectomyunderdifferentanesthetictechniquesvolatileanesthesiaversustotalintravenousanesthesia AT yeonjukim aprospectiverandomizedcomparisonofpostoperativepainandcomplicationsafterthyroidectomyunderdifferentanesthetictechniquesvolatileanesthesiaversustotalintravenousanesthesia AT seongsoochoi aprospectiverandomizedcomparisonofpostoperativepainandcomplicationsafterthyroidectomyunderdifferentanesthetictechniquesvolatileanesthesiaversustotalintravenousanesthesia AT jihoonpark aprospectiverandomizedcomparisonofpostoperativepainandcomplicationsafterthyroidectomyunderdifferentanesthetictechniquesvolatileanesthesiaversustotalintravenousanesthesia AT hanpark aprospectiverandomizedcomparisonofpostoperativepainandcomplicationsafterthyroidectomyunderdifferentanesthetictechniquesvolatileanesthesiaversustotalintravenousanesthesia AT kyungdonhahm aprospectiverandomizedcomparisonofpostoperativepainandcomplicationsafterthyroidectomyunderdifferentanesthetictechniquesvolatileanesthesiaversustotalintravenousanesthesia AT junyoungjo prospectiverandomizedcomparisonofpostoperativepainandcomplicationsafterthyroidectomyunderdifferentanesthetictechniquesvolatileanesthesiaversustotalintravenousanesthesia AT yeonjukim prospectiverandomizedcomparisonofpostoperativepainandcomplicationsafterthyroidectomyunderdifferentanesthetictechniquesvolatileanesthesiaversustotalintravenousanesthesia AT seongsoochoi prospectiverandomizedcomparisonofpostoperativepainandcomplicationsafterthyroidectomyunderdifferentanesthetictechniquesvolatileanesthesiaversustotalintravenousanesthesia AT jihoonpark prospectiverandomizedcomparisonofpostoperativepainandcomplicationsafterthyroidectomyunderdifferentanesthetictechniquesvolatileanesthesiaversustotalintravenousanesthesia AT hanpark prospectiverandomizedcomparisonofpostoperativepainandcomplicationsafterthyroidectomyunderdifferentanesthetictechniquesvolatileanesthesiaversustotalintravenousanesthesia AT kyungdonhahm prospectiverandomizedcomparisonofpostoperativepainandcomplicationsafterthyroidectomyunderdifferentanesthetictechniquesvolatileanesthesiaversustotalintravenousanesthesia |