Experimental studies of optoacoustic effect on the model of erythrocytes in the presence of carbon nanoparticles

Experimental model has been developed to study optoacoustic signal from model blood cells presented by polystyrene microspheres with nanoparticles. It was found out that nanoparticles due to their strong absorption of light significantly affect the coefficient of cellular optical absorption, while t...

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Main Authors: D. A. Kravchuk, D. V. Orda-Zhigulina
Format: Article
Language:Russian
Published: Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association" 2019-10-01
Series:Biomedical Photonics
Subjects:
Online Access:https://www.pdt-journal.com/jour/article/view/345
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author D. A. Kravchuk
D. V. Orda-Zhigulina
author_facet D. A. Kravchuk
D. V. Orda-Zhigulina
author_sort D. A. Kravchuk
collection DOAJ
description Experimental model has been developed to study optoacoustic signal from model blood cells presented by polystyrene microspheres with nanoparticles. It was found out that nanoparticles due to their strong absorption of light significantly affect the coefficient of cellular optical absorption, while the thermophysical parameters, namely the coefficient of thermal expansion, compressibility and isobaric specific heat of cells remain unchanged, since nanoparticles occupy a small intracellular volume compared to the cell volume. Optoacoustic signals were obtained using model solutions at various concentrations of cells and nanoparticles using 1064 nm laser. The results of experimental measurements using LIMO 100–532/1064-U system based on Nd:YAG showed that the amplitude of the optoacoustic signal increased without increasing the temperature in the laser area.
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institution Kabale University
issn 2413-9432
language Russian
publishDate 2019-10-01
publisher Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"
record_format Article
series Biomedical Photonics
spelling doaj-art-c17df0726c3d41c38d563336ef97a50a2025-08-20T04:00:13ZrusNon-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"Biomedical Photonics2413-94322019-10-0183111810.24931/2413-9432-2019-8-3-11-18181Experimental studies of optoacoustic effect on the model of erythrocytes in the presence of carbon nanoparticlesD. A. Kravchuk0D. V. Orda-Zhigulina1Southern Federal University, TaganrogOOO “Parametrika”, Taganrog; The Southern Scientific Centre of the Russian Academy of Sciences, Rostov-on-DonExperimental model has been developed to study optoacoustic signal from model blood cells presented by polystyrene microspheres with nanoparticles. It was found out that nanoparticles due to their strong absorption of light significantly affect the coefficient of cellular optical absorption, while the thermophysical parameters, namely the coefficient of thermal expansion, compressibility and isobaric specific heat of cells remain unchanged, since nanoparticles occupy a small intracellular volume compared to the cell volume. Optoacoustic signals were obtained using model solutions at various concentrations of cells and nanoparticles using 1064 nm laser. The results of experimental measurements using LIMO 100–532/1064-U system based on Nd:YAG showed that the amplitude of the optoacoustic signal increased without increasing the temperature in the laser area.https://www.pdt-journal.com/jour/article/view/345optoacoustic signalhematocritaggregationerythrocytesspectral power densitylaser
spellingShingle D. A. Kravchuk
D. V. Orda-Zhigulina
Experimental studies of optoacoustic effect on the model of erythrocytes in the presence of carbon nanoparticles
Biomedical Photonics
optoacoustic signal
hematocrit
aggregation
erythrocytes
spectral power density
laser
title Experimental studies of optoacoustic effect on the model of erythrocytes in the presence of carbon nanoparticles
title_full Experimental studies of optoacoustic effect on the model of erythrocytes in the presence of carbon nanoparticles
title_fullStr Experimental studies of optoacoustic effect on the model of erythrocytes in the presence of carbon nanoparticles
title_full_unstemmed Experimental studies of optoacoustic effect on the model of erythrocytes in the presence of carbon nanoparticles
title_short Experimental studies of optoacoustic effect on the model of erythrocytes in the presence of carbon nanoparticles
title_sort experimental studies of optoacoustic effect on the model of erythrocytes in the presence of carbon nanoparticles
topic optoacoustic signal
hematocrit
aggregation
erythrocytes
spectral power density
laser
url https://www.pdt-journal.com/jour/article/view/345
work_keys_str_mv AT dakravchuk experimentalstudiesofoptoacousticeffectonthemodeloferythrocytesinthepresenceofcarbonnanoparticles
AT dvordazhigulina experimentalstudiesofoptoacousticeffectonthemodeloferythrocytesinthepresenceofcarbonnanoparticles