Prevalence trends and risk factors for allergic rhinoconjunctivitis, asthma and eczema in the UK
Abstract Background Allergic rhinoconjunctivitis (ARC), asthma and eczema carry a substantial morbidity. These conditions often co-exist within the same individual and their prevalence can differ based on age, ethnicity and gender. Objectives Using a UK primary care database, we estimated the trends...
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BMC
2025-07-01
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| Series: | Allergy, Asthma & Clinical Immunology |
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| Online Access: | https://doi.org/10.1186/s13223-025-00975-2 |
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| author | Lavanya Diwakar Anuradhaa Subramanian Divya K. Shah Sumithra Subramaniam Victoria S. Pelly Sheila Greenfield David Moore Krishnarajah Nirantharakumar |
| author_facet | Lavanya Diwakar Anuradhaa Subramanian Divya K. Shah Sumithra Subramaniam Victoria S. Pelly Sheila Greenfield David Moore Krishnarajah Nirantharakumar |
| author_sort | Lavanya Diwakar |
| collection | DOAJ |
| description | Abstract Background Allergic rhinoconjunctivitis (ARC), asthma and eczema carry a substantial morbidity. These conditions often co-exist within the same individual and their prevalence can differ based on age, ethnicity and gender. Objectives Using a UK primary care database, we estimated the trends in prevalence over the last decade for ARC, asthma and eczema and associated risk factors. Methods Longitudinal cohort analysis of the health improvement (THIN) database between 1st Jan 2010 and 1st Jan 2019. Logistic regression analysis was used to explore risk factors for diagnosis of these conditions. Results An average of 4.17 million records per year were analysed, 19.4% were children and 49.75% were male. There was an increase in prevalence of ARC, asthma and eczema amongst adults during the study period, whereas ARC and asthma prevalence amongst children has fallen. By 2018, 1:8 adults and 1:14 children had ARC; asthma was diagnosed in 1:7 adults and 1:10 children whereas eczema was diagnosed in 1:6 adults and 1:4 children respectively. There were regional discrepancies in allergy prevalence across the UK. Caucasians generally had the highest rates of asthma and lower rates of ARC compared with other ethnic groups. Having other allergies substantially increases the odds of having asthma, eczema and ARC. Conclusion The population burden of ARC, asthma and eczema in the UK is substantial. These conditions are often associated with other allergies and can, therefore, be complex to manage. These data support calls for improvement of pathways of care for allergy patients in the UK. |
| format | Article |
| id | doaj-art-c17c4ac8805c43929d4c457bcf4e7017 |
| institution | Kabale University |
| issn | 1710-1492 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Allergy, Asthma & Clinical Immunology |
| spelling | doaj-art-c17c4ac8805c43929d4c457bcf4e70172025-08-20T04:02:56ZengBMCAllergy, Asthma & Clinical Immunology1710-14922025-07-012111910.1186/s13223-025-00975-2Prevalence trends and risk factors for allergic rhinoconjunctivitis, asthma and eczema in the UKLavanya Diwakar0Anuradhaa Subramanian1Divya K. Shah2Sumithra Subramaniam3Victoria S. Pelly4Sheila Greenfield5David Moore6Krishnarajah Nirantharakumar7Institute of Applied Health Research, University of BirminghamInstitute of Applied Health Research, University of BirminghamWellcome TrustWellcome TrustWellcome TrustInstitute of Applied Health Research, University of BirminghamInstitute of Applied Health Research, University of BirminghamInstitute of Applied Health Research, University of BirminghamAbstract Background Allergic rhinoconjunctivitis (ARC), asthma and eczema carry a substantial morbidity. These conditions often co-exist within the same individual and their prevalence can differ based on age, ethnicity and gender. Objectives Using a UK primary care database, we estimated the trends in prevalence over the last decade for ARC, asthma and eczema and associated risk factors. Methods Longitudinal cohort analysis of the health improvement (THIN) database between 1st Jan 2010 and 1st Jan 2019. Logistic regression analysis was used to explore risk factors for diagnosis of these conditions. Results An average of 4.17 million records per year were analysed, 19.4% were children and 49.75% were male. There was an increase in prevalence of ARC, asthma and eczema amongst adults during the study period, whereas ARC and asthma prevalence amongst children has fallen. By 2018, 1:8 adults and 1:14 children had ARC; asthma was diagnosed in 1:7 adults and 1:10 children whereas eczema was diagnosed in 1:6 adults and 1:4 children respectively. There were regional discrepancies in allergy prevalence across the UK. Caucasians generally had the highest rates of asthma and lower rates of ARC compared with other ethnic groups. Having other allergies substantially increases the odds of having asthma, eczema and ARC. Conclusion The population burden of ARC, asthma and eczema in the UK is substantial. These conditions are often associated with other allergies and can, therefore, be complex to manage. These data support calls for improvement of pathways of care for allergy patients in the UK.https://doi.org/10.1186/s13223-025-00975-2(6 max): allergic rhinoconjunctivitisAsthmaEczemaAllergyPrevalenceRisk factors |
| spellingShingle | Lavanya Diwakar Anuradhaa Subramanian Divya K. Shah Sumithra Subramaniam Victoria S. Pelly Sheila Greenfield David Moore Krishnarajah Nirantharakumar Prevalence trends and risk factors for allergic rhinoconjunctivitis, asthma and eczema in the UK Allergy, Asthma & Clinical Immunology (6 max): allergic rhinoconjunctivitis Asthma Eczema Allergy Prevalence Risk factors |
| title | Prevalence trends and risk factors for allergic rhinoconjunctivitis, asthma and eczema in the UK |
| title_full | Prevalence trends and risk factors for allergic rhinoconjunctivitis, asthma and eczema in the UK |
| title_fullStr | Prevalence trends and risk factors for allergic rhinoconjunctivitis, asthma and eczema in the UK |
| title_full_unstemmed | Prevalence trends and risk factors for allergic rhinoconjunctivitis, asthma and eczema in the UK |
| title_short | Prevalence trends and risk factors for allergic rhinoconjunctivitis, asthma and eczema in the UK |
| title_sort | prevalence trends and risk factors for allergic rhinoconjunctivitis asthma and eczema in the uk |
| topic | (6 max): allergic rhinoconjunctivitis Asthma Eczema Allergy Prevalence Risk factors |
| url | https://doi.org/10.1186/s13223-025-00975-2 |
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