Mycosis Fungoides: A Case Report
Mycosis fungoides is the most common primary cutaneous T-cell lymphoma and is recognized as one of the rare malignant skin neoplasms. Hypopigmented mycosis fungoides is a variant of mycosis fungoides, described in dark-skinned individual and Asian patients. We report a case of 32 years old Nepalese...
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| Format: | Article |
| Language: | English |
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Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)
2021-04-01
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| Series: | Nepal Journal of Dermatology, Venereology & Leprology |
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| Online Access: | https://www.nepjol.info/index.php/NJDVL/article/view/34167 |
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| _version_ | 1849227459418914816 |
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| author | Anisha Joshi Deeptara Pathak Thapa |
| author_facet | Anisha Joshi Deeptara Pathak Thapa |
| author_sort | Anisha Joshi |
| collection | DOAJ |
| description | Mycosis fungoides is the most common primary cutaneous T-cell lymphoma and is recognized as one of the rare malignant skin neoplasms. Hypopigmented mycosis fungoides is a variant of mycosis fungoides, described in dark-skinned individual and Asian patients. We report a case of 32 years old Nepalese female who had presented with multiple asymptomatic hypopigmented macules over the bilateral arms, thighs, abdomen, back of trunk and buttocks. Skin biopsy revealed few atypical cells (small/medium-sized, cerebriform nuclei with halo) confined to epidermis with epidermotropism. Immunohistochemistry showed CD3, CD4, CD5 and CD8 positivity. The patient was managed with topical steroids, oral methotrexate and phototherapy, and she is on regular follow up. As the disease has an indolent clinical course, long term follow up is necessary.
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| format | Article |
| id | doaj-art-c16934dce1ed4a79bdec3eba3f172a38 |
| institution | Kabale University |
| issn | 2091-0231 2091-167X |
| language | English |
| publishDate | 2021-04-01 |
| publisher | Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON) |
| record_format | Article |
| series | Nepal Journal of Dermatology, Venereology & Leprology |
| spelling | doaj-art-c16934dce1ed4a79bdec3eba3f172a382025-08-23T10:04:17ZengSociety of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)Nepal Journal of Dermatology, Venereology & Leprology2091-02312091-167X2021-04-0119110.3126/njdvl.v19i1.34167Mycosis Fungoides: A Case ReportAnisha Joshi0https://orcid.org/0000-0001-8316-3259Deeptara Pathak Thapa1Department of Dermatology, Nepal Medical College and Teaching Hospital, Kathmandu, NepalDepartment of Dermatology, Nepal Medical College and Teaching Hospital, Kathmandu, NepalMycosis fungoides is the most common primary cutaneous T-cell lymphoma and is recognized as one of the rare malignant skin neoplasms. Hypopigmented mycosis fungoides is a variant of mycosis fungoides, described in dark-skinned individual and Asian patients. We report a case of 32 years old Nepalese female who had presented with multiple asymptomatic hypopigmented macules over the bilateral arms, thighs, abdomen, back of trunk and buttocks. Skin biopsy revealed few atypical cells (small/medium-sized, cerebriform nuclei with halo) confined to epidermis with epidermotropism. Immunohistochemistry showed CD3, CD4, CD5 and CD8 positivity. The patient was managed with topical steroids, oral methotrexate and phototherapy, and she is on regular follow up. As the disease has an indolent clinical course, long term follow up is necessary. https://www.nepjol.info/index.php/NJDVL/article/view/34167HistopathologyImmunohistochemistryMycosis Fungoides |
| spellingShingle | Anisha Joshi Deeptara Pathak Thapa Mycosis Fungoides: A Case Report Nepal Journal of Dermatology, Venereology & Leprology Histopathology Immunohistochemistry Mycosis Fungoides |
| title | Mycosis Fungoides: A Case Report |
| title_full | Mycosis Fungoides: A Case Report |
| title_fullStr | Mycosis Fungoides: A Case Report |
| title_full_unstemmed | Mycosis Fungoides: A Case Report |
| title_short | Mycosis Fungoides: A Case Report |
| title_sort | mycosis fungoides a case report |
| topic | Histopathology Immunohistochemistry Mycosis Fungoides |
| url | https://www.nepjol.info/index.php/NJDVL/article/view/34167 |
| work_keys_str_mv | AT anishajoshi mycosisfungoidesacasereport AT deeptarapathakthapa mycosisfungoidesacasereport |