Cup-to-disc ratio measured clinically and via OCT in pediatric patients being monitored as glaucoma suspects for suspicious optic discs
PurposeCompare cup-to-disc ratio (CDR) measured by clinical assessment and optical coherence tomography (OCT) in pediatric eyes being monitored as glaucoma suspects for suspicious optic disc appearance.DesignRetrospective cross-sectional study.MethodsAn institutional study following 221 eyes from 12...
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Frontiers Media S.A.
2024-12-01
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| Series: | Frontiers in Ophthalmology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fopht.2024.1479286/full |
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| author | Caroline Maria Zimmermann Nur Cardakli Courtney Lynn Kraus |
| author_facet | Caroline Maria Zimmermann Nur Cardakli Courtney Lynn Kraus |
| author_sort | Caroline Maria Zimmermann |
| collection | DOAJ |
| description | PurposeCompare cup-to-disc ratio (CDR) measured by clinical assessment and optical coherence tomography (OCT) in pediatric eyes being monitored as glaucoma suspects for suspicious optic disc appearance.DesignRetrospective cross-sectional study.MethodsAn institutional study following 221 eyes from 122 unique pediatric glaucoma suspects being monitored due to increased or asymmetric appearance of CDR. Ophthalmologic findings, including visual acuity, intraocular pressure, CDR measured by clinical assessment, average retinal nerve fiber layer thickness, and average CDR measured by OCT, were recorded for each participant’s initial and final examinations. CDRs measured clinically and by OCT were compared at both initial and final presentations.ResultsAverage age at presentation was 9.0 years old (95% CI: 8.0-9.9), and mean length of follow-up was 5.0 years (95% CI: 5.4-4.5). At initial presentation, 53 eyes had CDRs recorded by both clinical assessment and OCT, and at final presentation, 93 eyes had CDRs measured by both modalities. CDR measured by OCT was significantly larger than CDR measured clinically on initial and final presentation (p=0.002, p<0.001).ConclusionsMeasurements of CDR by clinician assessment were significantly smaller than measurements obtained via OCT imaging. However, the average difference between CDR measured clinically and by OCT was <0.1. Thus, OCT may be a suitable way to measure CDR in pediatric glaucoma suspects, especially when clinical exam proves difficult. Further research is needed to assess CDR in glaucoma suspects using OCT longitudinally and in the context of other optic disc measurements, such as disc area. |
| format | Article |
| id | doaj-art-c15f65f6acdd46239ccd97bc6d0b871e |
| institution | OA Journals |
| issn | 2674-0826 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Ophthalmology |
| spelling | doaj-art-c15f65f6acdd46239ccd97bc6d0b871e2025-08-20T02:38:45ZengFrontiers Media S.A.Frontiers in Ophthalmology2674-08262024-12-01410.3389/fopht.2024.14792861479286Cup-to-disc ratio measured clinically and via OCT in pediatric patients being monitored as glaucoma suspects for suspicious optic discsCaroline Maria Zimmermann0Nur Cardakli1Courtney Lynn Kraus2Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, MD, United StatesWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, United StatesWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, United StatesPurposeCompare cup-to-disc ratio (CDR) measured by clinical assessment and optical coherence tomography (OCT) in pediatric eyes being monitored as glaucoma suspects for suspicious optic disc appearance.DesignRetrospective cross-sectional study.MethodsAn institutional study following 221 eyes from 122 unique pediatric glaucoma suspects being monitored due to increased or asymmetric appearance of CDR. Ophthalmologic findings, including visual acuity, intraocular pressure, CDR measured by clinical assessment, average retinal nerve fiber layer thickness, and average CDR measured by OCT, were recorded for each participant’s initial and final examinations. CDRs measured clinically and by OCT were compared at both initial and final presentations.ResultsAverage age at presentation was 9.0 years old (95% CI: 8.0-9.9), and mean length of follow-up was 5.0 years (95% CI: 5.4-4.5). At initial presentation, 53 eyes had CDRs recorded by both clinical assessment and OCT, and at final presentation, 93 eyes had CDRs measured by both modalities. CDR measured by OCT was significantly larger than CDR measured clinically on initial and final presentation (p=0.002, p<0.001).ConclusionsMeasurements of CDR by clinician assessment were significantly smaller than measurements obtained via OCT imaging. However, the average difference between CDR measured clinically and by OCT was <0.1. Thus, OCT may be a suitable way to measure CDR in pediatric glaucoma suspects, especially when clinical exam proves difficult. Further research is needed to assess CDR in glaucoma suspects using OCT longitudinally and in the context of other optic disc measurements, such as disc area.https://www.frontiersin.org/articles/10.3389/fopht.2024.1479286/fullcup-to-disc ratioglaucoma suspectpediatric glaucomaoptical coherence tomographypediatric |
| spellingShingle | Caroline Maria Zimmermann Nur Cardakli Courtney Lynn Kraus Cup-to-disc ratio measured clinically and via OCT in pediatric patients being monitored as glaucoma suspects for suspicious optic discs Frontiers in Ophthalmology cup-to-disc ratio glaucoma suspect pediatric glaucoma optical coherence tomography pediatric |
| title | Cup-to-disc ratio measured clinically and via OCT in pediatric patients being monitored as glaucoma suspects for suspicious optic discs |
| title_full | Cup-to-disc ratio measured clinically and via OCT in pediatric patients being monitored as glaucoma suspects for suspicious optic discs |
| title_fullStr | Cup-to-disc ratio measured clinically and via OCT in pediatric patients being monitored as glaucoma suspects for suspicious optic discs |
| title_full_unstemmed | Cup-to-disc ratio measured clinically and via OCT in pediatric patients being monitored as glaucoma suspects for suspicious optic discs |
| title_short | Cup-to-disc ratio measured clinically and via OCT in pediatric patients being monitored as glaucoma suspects for suspicious optic discs |
| title_sort | cup to disc ratio measured clinically and via oct in pediatric patients being monitored as glaucoma suspects for suspicious optic discs |
| topic | cup-to-disc ratio glaucoma suspect pediatric glaucoma optical coherence tomography pediatric |
| url | https://www.frontiersin.org/articles/10.3389/fopht.2024.1479286/full |
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