Synthesis, toxicity and antioxidant activity of phenolic benzimidazole derivatives: In vitro and in silico studies

Synthesis, toxicity and antioxidant activity of phenolic benzimidazole derivatives: In vitro and in silico studies

Benzimidazole derivatives have attracted significant attention due to their diverse pharmacological activities, including antimicrobial, anticancer, and antioxidant properties. This article reports the synthesis of two benzimidazole derivatives (2-(2-benzimidazolyl)phenol (3a) and 4-(1H-benzimidazol...

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Bibliographic Details
Main Authors: Mithun Rudrapal, Mohammad Mojammil, Azmal Farooque, Masoom Ansari, André M. de Oliveira, Johra Khan
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Chemical Physics Impact
Subjects:
Benzimidazole derivatives
Antioxidant activity
In vitro
Molecular docking
Molecular dynamics
DFT study
Online Access:http://www.sciencedirect.com/science/article/pii/S2667022425000635
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