Efficacy and safety of antiviral treatments for symptomatic COVID-19 outpatients: network meta-analysis and budget impact analysis

Efficacy and safety of antiviral treatments for symptomatic COVID-19 outpatients: network meta-analysis and budget impact analysis

IntroductionRemdesivir (RDV) and nirmatrelvir/ritonavir (NRM/RTV) are two antiviral agents for treating outpatient adults with mild to moderate symptomatic COVID-19 at high risk of developing a severe disease. The review objectives are to compare the efficacy and safety of these antivirals based on...

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Bibliographic Details
Main Authors: Giacomo Berti, Daniele Mengato, Honoria Ocagli, Gianmarco Chinellato, Maria Mazzitelli, Anna Maria Cattelan, Ileana Baldi, Francesca Venturini
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
COVID-19
remdesivir
nirmatrelvir-ritonavir
network meta-analysis
outpatient
cost-analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1537018/full
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