Unraveling immunosenescence in sepsis: from cellular mechanisms to therapeutics

Abstract Sepsis is a life-threatening multiple organ dysfunction resulting from a dysregulated host response to infection, and patients with sepsis always exhibit a state of immune disorder characterized by both overwhelming inflammation and immunosuppression. The aging of immune system, namely “imm...

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Bibliographic Details
Main Authors: Yanghanzhao Wang, Hao Zhang, Changhong Miao
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07714-w
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