Steamed panax notoginseng mitigates CA-MRSA USA300-induced necroptosis in human neutrophils

Steamed panax notoginseng mitigates CA-MRSA USA300-induced necroptosis in human neutrophils

BackgroundCommunity-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) disrupts innate immunity by inducing necroptosis in polymorphonuclear neutrophils (PMNs), a process linked to excessive inflammation and tissue damage. CA-MRSA releases virulence factors that enhance its pathogenici...

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Bibliographic Details
Main Authors: Lulu Zhang, Xiaoyu Feng, Hongsa An, Weifeng Yang, Yuwen Xia, Bo Wen, Haoran Zheng, Yihuan Chen, Yungchi Cheng, Chunyan Jiang, Cheng Lu, Yong Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
steamed Panax notoginseng
CA-MRSA
virulence factors
polymorphonuclear neutrophils
necroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1546652/full
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