Chlamydophila pneumoniae, Mycoplasma pneumoniae, and influenza in children with respiratory infections in Alexandria, Egypt
Introduction: Acute respiratory infections (ARI) are the leading cause of pediatric morbidity and mortality worldwide. Information about etiological agents of ARI in developing countries is still limited. Methodology: Throat swabs collected from children hospitalized with ARI between December 2009...
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The Journal of Infection in Developing Countries
2014-03-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/4458 |
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| author | Tiziana Grassi Fabiola Mancini Alessandra Ciervo Maria Fenicia Vescio Abeer Ghazal Housam Ashour Ezzeldin Saleh Mahmoud El Zalabani Isabella Donatelli Gamal El Sawaf Giovanni Rezza |
| author_facet | Tiziana Grassi Fabiola Mancini Alessandra Ciervo Maria Fenicia Vescio Abeer Ghazal Housam Ashour Ezzeldin Saleh Mahmoud El Zalabani Isabella Donatelli Gamal El Sawaf Giovanni Rezza |
| author_sort | Tiziana Grassi |
| collection | DOAJ |
| description | Introduction: Acute respiratory infections (ARI) are the leading cause of pediatric morbidity and mortality worldwide. Information about etiological agents of ARI in developing countries is still limited.
Methodology: Throat swabs collected from children hospitalized with ARI between December 2009 and May 2010 were investigated for Chlamydophila pneumoniae, Mycoplasma pneumoniae, and influenza viruses by molecular analyses.
Results: This study conducted in Alexandria, Egypt, was designed to determine the prevalence of several microorganisms in 156 children hospitalized with ARI. Overall, samples from 76 individuals (49%) were found to be positive for at least one pathogen, and 10 of them were positive for two agents. C. pneumoniae was the most commonly detected agent, followed by M. pneumonia and H1N1 pandemic influenza virus. Positivity for C. pneumoniae was associated with colder months and mild disease of the upper respiratory tract such as laryngitis.
Conclusions: Further studies are needed to identify other possible agents of ARI (e.g., RSV, adenoviruses, other bacterial infections) in this population and to better understand the causal role of atypical bacteria detected in respiratory samples.
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| format | Article |
| id | doaj-art-c14a3ec5a98e4fdca51eeb05c0ff0d16 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2014-03-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-c14a3ec5a98e4fdca51eeb05c0ff0d162025-08-20T02:27:20ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802014-03-0180310.3855/jidc.4458Chlamydophila pneumoniae, Mycoplasma pneumoniae, and influenza in children with respiratory infections in Alexandria, EgyptTiziana Grassi0Fabiola Mancini1Alessandra Ciervo2Maria Fenicia Vescio3Abeer Ghazal4Housam Ashour5Ezzeldin Saleh6Mahmoud El Zalabani7Isabella Donatelli8Gamal El Sawaf9Giovanni Rezza10National Public Health Institute, Rome, ItalyNational Public Health Institute, Rome, ItalyNational Public Health Institute, Rome, ItalyNational Public Health Institute, Rome, ItalyMedical Research Institute, Alexandria University, Alexandria, EgyptFaculty of Medicine, Alexandria University, Alexandria, EgyptMedical Research Institute, Alexandria University, Alexandria, EgyptFaculty of Medicine, Alexandria University, Alexandria, EgyptNational Public Health Institute, Rome, ItalyMedical Research Institute, Alexandria University, Alexandria, EgyptNational Public Health Institute, Rome, ItalyIntroduction: Acute respiratory infections (ARI) are the leading cause of pediatric morbidity and mortality worldwide. Information about etiological agents of ARI in developing countries is still limited. Methodology: Throat swabs collected from children hospitalized with ARI between December 2009 and May 2010 were investigated for Chlamydophila pneumoniae, Mycoplasma pneumoniae, and influenza viruses by molecular analyses. Results: This study conducted in Alexandria, Egypt, was designed to determine the prevalence of several microorganisms in 156 children hospitalized with ARI. Overall, samples from 76 individuals (49%) were found to be positive for at least one pathogen, and 10 of them were positive for two agents. C. pneumoniae was the most commonly detected agent, followed by M. pneumonia and H1N1 pandemic influenza virus. Positivity for C. pneumoniae was associated with colder months and mild disease of the upper respiratory tract such as laryngitis. Conclusions: Further studies are needed to identify other possible agents of ARI (e.g., RSV, adenoviruses, other bacterial infections) in this population and to better understand the causal role of atypical bacteria detected in respiratory samples. https://jidc.org/index.php/journal/article/view/4458Chlamydophila pneumoniaeMycoplasma pneumoniaeinfluenza virusesacute respiratory infectionsreal-time PCREgypt |
| spellingShingle | Tiziana Grassi Fabiola Mancini Alessandra Ciervo Maria Fenicia Vescio Abeer Ghazal Housam Ashour Ezzeldin Saleh Mahmoud El Zalabani Isabella Donatelli Gamal El Sawaf Giovanni Rezza Chlamydophila pneumoniae, Mycoplasma pneumoniae, and influenza in children with respiratory infections in Alexandria, Egypt Journal of Infection in Developing Countries Chlamydophila pneumoniae Mycoplasma pneumoniae influenza viruses acute respiratory infections real-time PCR Egypt |
| title | Chlamydophila pneumoniae, Mycoplasma pneumoniae, and influenza in children with respiratory infections in Alexandria, Egypt |
| title_full | Chlamydophila pneumoniae, Mycoplasma pneumoniae, and influenza in children with respiratory infections in Alexandria, Egypt |
| title_fullStr | Chlamydophila pneumoniae, Mycoplasma pneumoniae, and influenza in children with respiratory infections in Alexandria, Egypt |
| title_full_unstemmed | Chlamydophila pneumoniae, Mycoplasma pneumoniae, and influenza in children with respiratory infections in Alexandria, Egypt |
| title_short | Chlamydophila pneumoniae, Mycoplasma pneumoniae, and influenza in children with respiratory infections in Alexandria, Egypt |
| title_sort | chlamydophila pneumoniae mycoplasma pneumoniae and influenza in children with respiratory infections in alexandria egypt |
| topic | Chlamydophila pneumoniae Mycoplasma pneumoniae influenza viruses acute respiratory infections real-time PCR Egypt |
| url | https://jidc.org/index.php/journal/article/view/4458 |
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