Applications of Platelet-Rich Fibrin (PRF) Membranes Alone or in Combination with Biomimetic Materials in Oral Regeneration: A Narrative Review
Platelet-rich fibrin (PRF) membranes are a biomaterial derived from the patient’s own blood, used in different medical and dental areas for their ability to promote healing, tissue regeneration, and reduce inflammation. They are obtained by centrifuging the blood, which separates the components and...
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MDPI AG
2025-03-01
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| author | Javier Valenzuela-Mencia Francisco Javier Manzano-Moreno |
| author_facet | Javier Valenzuela-Mencia Francisco Javier Manzano-Moreno |
| author_sort | Javier Valenzuela-Mencia |
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| description | Platelet-rich fibrin (PRF) membranes are a biomaterial derived from the patient’s own blood, used in different medical and dental areas for their ability to promote healing, tissue regeneration, and reduce inflammation. They are obtained by centrifuging the blood, which separates the components and concentrates the platelets and growth factors in a fibrin matrix. This material is then moulded into a membrane that can be applied directly to tissues. The use of these PRF membranes is often associated with the use of different biomimetic materials such as deproteinized bovine bone mineral (DBBM), β-tricalcium phosphate (β-TCP), enamel matrix derivative (EMD), and hydroxyapatite (HA). Different indications of PRF membranes have been proposed, like alveolar ridge preservation, alveolar ridge augmentation, guided tissue regeneration (GTR), and sinus floor augmentation. The aim of this narrative review is to check the state-of-the-art and to analyze the existing gaps in the use of PRF membranes in combination with biomimetic materials in alveolar ridge preservation, alveolar ridge augmentation, guided tissue regeneration (GTR), and sinus floor augmentation. |
| format | Article |
| id | doaj-art-c13e795fda4d4cdc921489ee584a0568 |
| institution | OA Journals |
| issn | 2313-7673 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomimetics |
| spelling | doaj-art-c13e795fda4d4cdc921489ee584a05682025-08-20T02:11:01ZengMDPI AGBiomimetics2313-76732025-03-0110317210.3390/biomimetics10030172Applications of Platelet-Rich Fibrin (PRF) Membranes Alone or in Combination with Biomimetic Materials in Oral Regeneration: A Narrative ReviewJavier Valenzuela-Mencia0Francisco Javier Manzano-Moreno1Department of Stomatology, Colegio Máximo de Cartuja s/n, University of Granada, 18071 Granada, SpainDepartment of Stomatology, Colegio Máximo de Cartuja s/n, University of Granada, 18071 Granada, SpainPlatelet-rich fibrin (PRF) membranes are a biomaterial derived from the patient’s own blood, used in different medical and dental areas for their ability to promote healing, tissue regeneration, and reduce inflammation. They are obtained by centrifuging the blood, which separates the components and concentrates the platelets and growth factors in a fibrin matrix. This material is then moulded into a membrane that can be applied directly to tissues. The use of these PRF membranes is often associated with the use of different biomimetic materials such as deproteinized bovine bone mineral (DBBM), β-tricalcium phosphate (β-TCP), enamel matrix derivative (EMD), and hydroxyapatite (HA). Different indications of PRF membranes have been proposed, like alveolar ridge preservation, alveolar ridge augmentation, guided tissue regeneration (GTR), and sinus floor augmentation. The aim of this narrative review is to check the state-of-the-art and to analyze the existing gaps in the use of PRF membranes in combination with biomimetic materials in alveolar ridge preservation, alveolar ridge augmentation, guided tissue regeneration (GTR), and sinus floor augmentation.https://www.mdpi.com/2313-7673/10/3/172plasmamembranesfibrinbiomimeticbone regeneration |
| spellingShingle | Javier Valenzuela-Mencia Francisco Javier Manzano-Moreno Applications of Platelet-Rich Fibrin (PRF) Membranes Alone or in Combination with Biomimetic Materials in Oral Regeneration: A Narrative Review Biomimetics plasma membranes fibrin biomimetic bone regeneration |
| title | Applications of Platelet-Rich Fibrin (PRF) Membranes Alone or in Combination with Biomimetic Materials in Oral Regeneration: A Narrative Review |
| title_full | Applications of Platelet-Rich Fibrin (PRF) Membranes Alone or in Combination with Biomimetic Materials in Oral Regeneration: A Narrative Review |
| title_fullStr | Applications of Platelet-Rich Fibrin (PRF) Membranes Alone or in Combination with Biomimetic Materials in Oral Regeneration: A Narrative Review |
| title_full_unstemmed | Applications of Platelet-Rich Fibrin (PRF) Membranes Alone or in Combination with Biomimetic Materials in Oral Regeneration: A Narrative Review |
| title_short | Applications of Platelet-Rich Fibrin (PRF) Membranes Alone or in Combination with Biomimetic Materials in Oral Regeneration: A Narrative Review |
| title_sort | applications of platelet rich fibrin prf membranes alone or in combination with biomimetic materials in oral regeneration a narrative review |
| topic | plasma membranes fibrin biomimetic bone regeneration |
| url | https://www.mdpi.com/2313-7673/10/3/172 |
| work_keys_str_mv | AT javiervalenzuelamencia applicationsofplateletrichfibrinprfmembranesaloneorincombinationwithbiomimeticmaterialsinoralregenerationanarrativereview AT franciscojaviermanzanomoreno applicationsofplateletrichfibrinprfmembranesaloneorincombinationwithbiomimeticmaterialsinoralregenerationanarrativereview |