Acute infectious purpura fulminans: case report of a medical emergency
Abstract. Background. Purpura fulminans (PF), characterized by the sudden onset of large, rapidly spreading hemorrhagic skin infarctions and associated disseminated intravascular coagulation, is an uncommon medical emergency. Early recognition, prompt antibiotic therapy, and intensive supportive car...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Health/LWW
2023-06-01
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| Series: | Emergency and Critical Care Medicine |
| Online Access: | http://journals.lww.com/10.1097/EC9.0000000000000067 |
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| author | Xueying Li Yaqian Ma Qichao Sun Ruihan Hu Zhi Liu Xiaowei Liu |
| author_facet | Xueying Li Yaqian Ma Qichao Sun Ruihan Hu Zhi Liu Xiaowei Liu |
| author_sort | Xueying Li |
| collection | DOAJ |
| description | Abstract. Background. Purpura fulminans (PF), characterized by the sudden onset of large, rapidly spreading hemorrhagic skin infarctions and associated disseminated intravascular coagulation, is an uncommon medical emergency. Early recognition, prompt antibiotic therapy, and intensive supportive care are essential to reduce the mortality rate of this disease.
Case Presentation. We report the case of a 28-year-old Chinese man with acute infectious PF. He initially presented with a fever, which rapidly progressed to septic shock, followed by skin lesions and disseminated intravascular coagulation. Computed tomography imaging revealed superior and inferior mesenteric vein thromboses. Although the etiology of the patient’s infection was unclear, the patient received early fluid resuscitation, empiric antibiotic therapy, and blood product replacement, which resulted in gradual clinical improvement.
Conclusion. Sepsis-associated PF may be reversible with timely empirical therapeutic interventions; however, the severity of PF should not be underestimated, and treatment should be tailored to individual patients. |
| format | Article |
| id | doaj-art-c132cdce13104c778ba956cdc2c8bc06 |
| institution | OA Journals |
| issn | 2097-0617 2693-860X |
| language | English |
| publishDate | 2023-06-01 |
| publisher | Wolters Kluwer Health/LWW |
| record_format | Article |
| series | Emergency and Critical Care Medicine |
| spelling | doaj-art-c132cdce13104c778ba956cdc2c8bc062025-08-20T01:54:12ZengWolters Kluwer Health/LWWEmergency and Critical Care Medicine2097-06172693-860X2023-06-0132848710.1097/EC9.0000000000000067202306000-00009Acute infectious purpura fulminans: case report of a medical emergencyXueying Li0Yaqian Ma1Qichao Sun2Ruihan Hu3Zhi Liu4Xiaowei Liu5Department of Emergency Medicine, the First Affiliated Hospital, China Medical University, Shenyang, Liaoning, China.Department of Emergency Medicine, the First Affiliated Hospital, China Medical University, Shenyang, Liaoning, China.Department of Emergency Medicine, the First Affiliated Hospital, China Medical University, Shenyang, Liaoning, China.Department of Emergency Medicine, the First Affiliated Hospital, China Medical University, Shenyang, Liaoning, China.Department of Emergency Medicine, the First Affiliated Hospital, China Medical University, Shenyang, Liaoning, China.Department of Emergency Medicine, the First Affiliated Hospital, China Medical University, Shenyang, Liaoning, China.Abstract. Background. Purpura fulminans (PF), characterized by the sudden onset of large, rapidly spreading hemorrhagic skin infarctions and associated disseminated intravascular coagulation, is an uncommon medical emergency. Early recognition, prompt antibiotic therapy, and intensive supportive care are essential to reduce the mortality rate of this disease. Case Presentation. We report the case of a 28-year-old Chinese man with acute infectious PF. He initially presented with a fever, which rapidly progressed to septic shock, followed by skin lesions and disseminated intravascular coagulation. Computed tomography imaging revealed superior and inferior mesenteric vein thromboses. Although the etiology of the patient’s infection was unclear, the patient received early fluid resuscitation, empiric antibiotic therapy, and blood product replacement, which resulted in gradual clinical improvement. Conclusion. Sepsis-associated PF may be reversible with timely empirical therapeutic interventions; however, the severity of PF should not be underestimated, and treatment should be tailored to individual patients.http://journals.lww.com/10.1097/EC9.0000000000000067 |
| spellingShingle | Xueying Li Yaqian Ma Qichao Sun Ruihan Hu Zhi Liu Xiaowei Liu Acute infectious purpura fulminans: case report of a medical emergency Emergency and Critical Care Medicine |
| title | Acute infectious purpura fulminans: case report of a medical emergency |
| title_full | Acute infectious purpura fulminans: case report of a medical emergency |
| title_fullStr | Acute infectious purpura fulminans: case report of a medical emergency |
| title_full_unstemmed | Acute infectious purpura fulminans: case report of a medical emergency |
| title_short | Acute infectious purpura fulminans: case report of a medical emergency |
| title_sort | acute infectious purpura fulminans case report of a medical emergency |
| url | http://journals.lww.com/10.1097/EC9.0000000000000067 |
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