A hybrid machine learning model with attention mechanism and multidimensional multivariate feature coding for essential gene prediction

A hybrid machine learning model with attention mechanism and multidimensional multivariate feature coding for essential gene prediction

Abstract Background Essential genes are crucial for the development, inheritance, and survival of species. The exploration of these genes can unravel the complex mechanisms and fundamental life processes and identify potential therapeutic targets for various diseases. Therefore, the identification o...

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Bibliographic Details
Main Authors: Wu Yan, Fu Yu, Li Tan, Li Mengshan, Xie Xiaojun, Zhou Weihong, Sheng Sheng, Wang Jun, Wu Fu-an
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Biology
Subjects:
Essential gene
Machine learning
Attention mechanism
LSTM
CNN
Feature coding
Online Access:https://doi.org/10.1186/s12915-025-02209-8
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