Hippo/YAP signaling’s multifaceted crosstalk in cancer

Hippo/YAP signaling’s multifaceted crosstalk in cancer

The Hippo/yes-associated protein (YAP) signaling is an evolutionarily conserved regulator in organ size control, which plays pivotal roles in cell proliferation, differentiation, apoptosis, and tissue regeneration. In cancer, dysregulation of Hippo/YAP signaling is typically recognized as one of the...

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Bibliographic Details
Main Authors: Jie Zhang, Haipeng Wu, Xinxin Ren, Zhuoshi Chen, Siyu Ye, Shuchang Chen, Jie Fang, Qirou Wu, Tiejun Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Hippo/YAP signaling
signaling pathway
crosstalk
cancer
therapeutic target
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1595362/full
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