Green Synthesis of iron Nanoparticles by Aqueous Extract of Zingiber officinale: Characterization and inhibitory effect on Escherichia coli investigated

Purpose: The goal of biomedical researchers is to overcome harmful bacteria' resistance to antibiotics by developing new active chemicals quickly, cheaply, easily, and environmentally. Materials and Methods: In this instance, iron nanoparticles (Fe-NPs) were created using a green method by...

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Main Authors: Hind Ibrahim Khaleel, Nada Qasim Kadhim, Ameer Qasim Abdalrida
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2025-07-01
Series:Frontiers in Biomedical Technologies
Subjects:
Online Access:https://fbt.tums.ac.ir/index.php/fbt/article/view/952
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author Hind Ibrahim Khaleel
Nada Qasim Kadhim
Ameer Qasim Abdalrida
author_facet Hind Ibrahim Khaleel
Nada Qasim Kadhim
Ameer Qasim Abdalrida
author_sort Hind Ibrahim Khaleel
collection DOAJ
description Purpose: The goal of biomedical researchers is to overcome harmful bacteria' resistance to antibiotics by developing new active chemicals quickly, cheaply, easily, and environmentally. Materials and Methods: In this instance, iron nanoparticles (Fe-NPs) were created using a green method by mixing an equal volume of Zingiber officinale aqueous extract with a 100 ml solution of ferrous chloride tetrahydrate (FeCl2.4H2O (0.4 M)). The distinctive dark brown color shift of the mixture indicated the production of Fe-NPs. Results: This suggests that the nanocomposite was created and the reaction occurred. FT-IR, TEM, and UV-Vis spectroscopy were utilized to analyze phytosynthesized Fe-NPs. Overall, the phytosynthesized Fe-NPs show activities that enable their use in various biomedical and biotechnological applications. Additionally, the antimicrobial effect was investigated against Gram-negative bacteria (Escherichia coli). Conclusion: The antibacterial activity of E. coli was determined, and the highest zone of inhibition was observed at the concentration of 100 μg/mL.
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issn 2345-5837
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series Frontiers in Biomedical Technologies
spelling doaj-art-c129631be33b48719f91ed73afa8dca12025-08-20T03:40:33ZengTehran University of Medical SciencesFrontiers in Biomedical Technologies2345-58372025-07-0112310.18502/fbt.v12i3.19176Green Synthesis of iron Nanoparticles by Aqueous Extract of Zingiber officinale: Characterization and inhibitory effect on Escherichia coli investigatedHind Ibrahim Khaleel0Nada Qasim Kadhim1Ameer Qasim Abdalrida2Department of Chemistry, Collage of Science, Baghdad University, Department of Chemistry, Collage of Science, Baghdad University, Ibn Sina University of medical and pharmaceutical Sciences.Department of Chemistry, Collage of Science, Baghdad University, Baghdad, IraqCollege of Medicine, Ibn Sina University of Medical and Pharmaceutical Sciences, Baghdad, Iraq Purpose: The goal of biomedical researchers is to overcome harmful bacteria' resistance to antibiotics by developing new active chemicals quickly, cheaply, easily, and environmentally. Materials and Methods: In this instance, iron nanoparticles (Fe-NPs) were created using a green method by mixing an equal volume of Zingiber officinale aqueous extract with a 100 ml solution of ferrous chloride tetrahydrate (FeCl2.4H2O (0.4 M)). The distinctive dark brown color shift of the mixture indicated the production of Fe-NPs. Results: This suggests that the nanocomposite was created and the reaction occurred. FT-IR, TEM, and UV-Vis spectroscopy were utilized to analyze phytosynthesized Fe-NPs. Overall, the phytosynthesized Fe-NPs show activities that enable their use in various biomedical and biotechnological applications. Additionally, the antimicrobial effect was investigated against Gram-negative bacteria (Escherichia coli). Conclusion: The antibacterial activity of E. coli was determined, and the highest zone of inhibition was observed at the concentration of 100 μg/mL. https://fbt.tums.ac.ir/index.php/fbt/article/view/952NanoparticlesGreen SynthesisIron Oxide NanoparticlesAntimicrobial Activity
spellingShingle Hind Ibrahim Khaleel
Nada Qasim Kadhim
Ameer Qasim Abdalrida
Green Synthesis of iron Nanoparticles by Aqueous Extract of Zingiber officinale: Characterization and inhibitory effect on Escherichia coli investigated
Frontiers in Biomedical Technologies
Nanoparticles
Green Synthesis
Iron Oxide Nanoparticles
Antimicrobial Activity
title Green Synthesis of iron Nanoparticles by Aqueous Extract of Zingiber officinale: Characterization and inhibitory effect on Escherichia coli investigated
title_full Green Synthesis of iron Nanoparticles by Aqueous Extract of Zingiber officinale: Characterization and inhibitory effect on Escherichia coli investigated
title_fullStr Green Synthesis of iron Nanoparticles by Aqueous Extract of Zingiber officinale: Characterization and inhibitory effect on Escherichia coli investigated
title_full_unstemmed Green Synthesis of iron Nanoparticles by Aqueous Extract of Zingiber officinale: Characterization and inhibitory effect on Escherichia coli investigated
title_short Green Synthesis of iron Nanoparticles by Aqueous Extract of Zingiber officinale: Characterization and inhibitory effect on Escherichia coli investigated
title_sort green synthesis of iron nanoparticles by aqueous extract of zingiber officinale characterization and inhibitory effect on escherichia coli investigated
topic Nanoparticles
Green Synthesis
Iron Oxide Nanoparticles
Antimicrobial Activity
url https://fbt.tums.ac.ir/index.php/fbt/article/view/952
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AT ameerqasimabdalrida greensynthesisofironnanoparticlesbyaqueousextractofzingiberofficinalecharacterizationandinhibitoryeffectonescherichiacoliinvestigated