Green Synthesis of iron Nanoparticles by Aqueous Extract of Zingiber officinale: Characterization and inhibitory effect on Escherichia coli investigated

Purpose: The goal of biomedical researchers is to overcome harmful bacteria' resistance to antibiotics by developing new active chemicals quickly, cheaply, easily, and environmentally. Materials and Methods: In this instance, iron nanoparticles (Fe-NPs) were created using a green method by...

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Bibliographic Details
Main Authors: Hind Ibrahim Khaleel, Nada Qasim Kadhim, Ameer Qasim Abdalrida
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2025-07-01
Series:Frontiers in Biomedical Technologies
Subjects:
Online Access:https://fbt.tums.ac.ir/index.php/fbt/article/view/952
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Summary:Purpose: The goal of biomedical researchers is to overcome harmful bacteria' resistance to antibiotics by developing new active chemicals quickly, cheaply, easily, and environmentally. Materials and Methods: In this instance, iron nanoparticles (Fe-NPs) were created using a green method by mixing an equal volume of Zingiber officinale aqueous extract with a 100 ml solution of ferrous chloride tetrahydrate (FeCl2.4H2O (0.4 M)). The distinctive dark brown color shift of the mixture indicated the production of Fe-NPs. Results: This suggests that the nanocomposite was created and the reaction occurred. FT-IR, TEM, and UV-Vis spectroscopy were utilized to analyze phytosynthesized Fe-NPs. Overall, the phytosynthesized Fe-NPs show activities that enable their use in various biomedical and biotechnological applications. Additionally, the antimicrobial effect was investigated against Gram-negative bacteria (Escherichia coli). Conclusion: The antibacterial activity of E. coli was determined, and the highest zone of inhibition was observed at the concentration of 100 μg/mL.
ISSN:2345-5837