Fibroblast Growth Factor 21 Promotes Vascular Smooth Muscle Cell Contractile Polarization via p38 Mitogen-Activated Protein Kinase-Promoted Serum Response Factor Phosphorylation

Fibroblast Growth Factor 21 Promotes Vascular Smooth Muscle Cell Contractile Polarization via p38 Mitogen-Activated Protein Kinase-Promoted Serum Response Factor Phosphorylation

Phenotypic abnormalities in vascular smooth muscle cells (VSMCs) are believed to play essential roles in the progression of vascular diseases. Here, we explored the impact of fibroblast growth factor 21 (FGF21) on the phenotypic transition of VSMCs. Our findings revealed that FGF21 expression was su...

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Main Authors: Mengmeng Zhu, Wenya Zhu, Jianyuan Pan, Ziyi Chen, Yali Yan, Shengnan Wang, Tingting Zhang, Xiaoxiao Yang, Hongmei Xu, Xiangyong Kong, Hao Hu, Suowen Xu, Xia Zhang, Buchun Zhang, Chenzhong Liao, Yajun Duan, Shu Yang, Yuanli Chen
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2025-01-01
Series:Research
Online Access:https://spj.science.org/doi/10.34133/research.0815
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