BREAST CANCER AND PREGNANCY

25 evidenced based clinical practice guidelines for fertility preservation in cancer patients exist. Breast Cancer in Pregnancy is a rare problem but the incidence is growing, because pregnancy will be delayed in elder age groups. Diagnosis of Breast Cancer is often delayed. If there is a mass, you...

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Main Authors: Ch. Dadak, A. D. Makatsariya
Format: Article
Language:Russian
Published: IRBIS LLC 2017-06-01
Series:Акушерство, гинекология и репродукция
Subjects:
Online Access:https://www.gynecology.su/jour/article/view/397
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author Ch. Dadak
A. D. Makatsariya
author_facet Ch. Dadak
A. D. Makatsariya
author_sort Ch. Dadak
collection DOAJ
description 25 evidenced based clinical practice guidelines for fertility preservation in cancer patients exist. Breast Cancer in Pregnancy is a rare problem but the incidence is growing, because pregnancy will be delayed in elder age groups. Diagnosis of Breast Cancer is often delayed. If there is a mass, you have to do at first an ultrasound and than mammography if it is necessary. A tumor should be biopsied. Each kind of surgery is possible. Sentinel lymphnode dissection is controversial discussed. It is because of the blue dye, because this substance is not allowed during pregnancy. Technetium is allowed, but will be not accepted by the mother, because of fear of radiance. Radiation and hormonal treatment should be postponed after pregnancy. Chemotherapy can be done after 16 week of gestation. Delivery should not be in the first 3 weeks after chemotherapy, because the nadir of white blood cells should not be at the time of delivery to avoid infection. The fetal outcome is quite normal except weight, because of preterm delivery and growth retardation. Termination of pregnancy will not optimize the cancer prognosis. Pregnancy after breast cancer treatment is possible, perhaps with better prognosis, but that can be due to the healthy mother effect. Because the most recurrence are in the first two years, women should wait 2 years and cryopreservation of ovarian tissue, eggs or embryos before chemotherapy should be done.
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spelling doaj-art-c11cb520b08b42ab852c8d7b79c5e2472025-08-20T03:57:36ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942017-06-01111748010.17749/2313-7347.2017.11.1.074-080381BREAST CANCER AND PREGNANCYCh. Dadak0A. D. Makatsariya1Medical University of ViennaI.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia25 evidenced based clinical practice guidelines for fertility preservation in cancer patients exist. Breast Cancer in Pregnancy is a rare problem but the incidence is growing, because pregnancy will be delayed in elder age groups. Diagnosis of Breast Cancer is often delayed. If there is a mass, you have to do at first an ultrasound and than mammography if it is necessary. A tumor should be biopsied. Each kind of surgery is possible. Sentinel lymphnode dissection is controversial discussed. It is because of the blue dye, because this substance is not allowed during pregnancy. Technetium is allowed, but will be not accepted by the mother, because of fear of radiance. Radiation and hormonal treatment should be postponed after pregnancy. Chemotherapy can be done after 16 week of gestation. Delivery should not be in the first 3 weeks after chemotherapy, because the nadir of white blood cells should not be at the time of delivery to avoid infection. The fetal outcome is quite normal except weight, because of preterm delivery and growth retardation. Termination of pregnancy will not optimize the cancer prognosis. Pregnancy after breast cancer treatment is possible, perhaps with better prognosis, but that can be due to the healthy mother effect. Because the most recurrence are in the first two years, women should wait 2 years and cryopreservation of ovarian tissue, eggs or embryos before chemotherapy should be done.https://www.gynecology.su/jour/article/view/397breast cancerpregnancytumorchemotherapycryopreservation.
spellingShingle Ch. Dadak
A. D. Makatsariya
BREAST CANCER AND PREGNANCY
Акушерство, гинекология и репродукция
breast cancer
pregnancy
tumor
chemotherapy
cryopreservation.
title BREAST CANCER AND PREGNANCY
title_full BREAST CANCER AND PREGNANCY
title_fullStr BREAST CANCER AND PREGNANCY
title_full_unstemmed BREAST CANCER AND PREGNANCY
title_short BREAST CANCER AND PREGNANCY
title_sort breast cancer and pregnancy
topic breast cancer
pregnancy
tumor
chemotherapy
cryopreservation.
url https://www.gynecology.su/jour/article/view/397
work_keys_str_mv AT chdadak breastcancerandpregnancy
AT admakatsariya breastcancerandpregnancy