Profile of proinflammatory markers in pregnant women who died of severe COVID-19
Introduction: In December 2019, four cases of pneumonia of unknown origin were reported to the World Health Organization (WHO) in China, caused by SARS-CoV-2. In March 2020, the WHO declared the beginning of the COVID-19 pandemic. In COVID-19, a relevant component is vulnerable groups, such as pregn...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Permanyer
2025-01-01
|
| Series: | Revista Médica del Hospital General de México |
| Subjects: | |
| Online Access: | https://www.hospitalgeneral.mx/frame_eng.php?id=239 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1825200121688621056 |
|---|---|
| author | Pablo B. Bautista-García Mariana Bahena-Campos Diana H. Alcántara-Rosas |
| author_facet | Pablo B. Bautista-García Mariana Bahena-Campos Diana H. Alcántara-Rosas |
| author_sort | Pablo B. Bautista-García |
| collection | DOAJ |
| description | Introduction: In December 2019, four cases of pneumonia of unknown origin were reported to the World Health Organization (WHO) in China, caused by SARS-CoV-2. In March 2020, the WHO declared the beginning of the COVID-19 pandemic. In COVID-19, a relevant component is vulnerable groups, such as pregnant women representing a special group due to their high mortality secondary to COVID-19. Objective: Describe the association between proinflammatory markers and survival in pregnant women with critical COVID-19, in the intensive care unit (ICU) of the General Hospital of Cholula from January 2020 to 2021. Materials and methods: This is an analytical and cross-sectional observational retrospective study conducted on pregnant women admitted to the ICU. Pregnant women, between 18 and 35 years old, at 30-40 weeks gestation diagnosed with critical COVID-19 were included. Results: It was observed that pregnant women with critical COVID-19 showed increased values of C-reactive protein, leukocytes, D-dimer, and DHL compared to surviving pregnant patients with critical COVID-19; however, no statistical significance was observed for platelet number and fibrinogen. Conclusion: In the case of pregnant women who died from critical COVID-19, there was a significant increase in inflammatory markers, in contrast to what was observed in other studies, no changes in the number of platelets or fibrinogen were observed.
|
| format | Article |
| id | doaj-art-c119c9d79f5c4676a5b206ddf36b5b95 |
| institution | Kabale University |
| issn | 0185-1063 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Permanyer |
| record_format | Article |
| series | Revista Médica del Hospital General de México |
| spelling | doaj-art-c119c9d79f5c4676a5b206ddf36b5b952025-02-07T20:38:57ZengPermanyerRevista Médica del Hospital General de México0185-10632025-01-01881Profile of proinflammatory markers in pregnant women who died of severe COVID-19Pablo B. Bautista-García0Mariana Bahena-Campos1Diana H. Alcántara-Rosas2Department of Internal Medicine, Hospital General de Cholula, Cholula, Puebla, MéxicoAdult Intensive Care Unit, Hospital General de Cholula, Cholula, Puebla, MéxicoAdult Intensive Care Unit, Hospital General de Cholula, Cholula, Puebla, MéxicoIntroduction: In December 2019, four cases of pneumonia of unknown origin were reported to the World Health Organization (WHO) in China, caused by SARS-CoV-2. In March 2020, the WHO declared the beginning of the COVID-19 pandemic. In COVID-19, a relevant component is vulnerable groups, such as pregnant women representing a special group due to their high mortality secondary to COVID-19. Objective: Describe the association between proinflammatory markers and survival in pregnant women with critical COVID-19, in the intensive care unit (ICU) of the General Hospital of Cholula from January 2020 to 2021. Materials and methods: This is an analytical and cross-sectional observational retrospective study conducted on pregnant women admitted to the ICU. Pregnant women, between 18 and 35 years old, at 30-40 weeks gestation diagnosed with critical COVID-19 were included. Results: It was observed that pregnant women with critical COVID-19 showed increased values of C-reactive protein, leukocytes, D-dimer, and DHL compared to surviving pregnant patients with critical COVID-19; however, no statistical significance was observed for platelet number and fibrinogen. Conclusion: In the case of pregnant women who died from critical COVID-19, there was a significant increase in inflammatory markers, in contrast to what was observed in other studies, no changes in the number of platelets or fibrinogen were observed. https://www.hospitalgeneral.mx/frame_eng.php?id=239Critical COVID-19. Pregnant women. Proinflammatory cytokines. |
| spellingShingle | Pablo B. Bautista-García Mariana Bahena-Campos Diana H. Alcántara-Rosas Profile of proinflammatory markers in pregnant women who died of severe COVID-19 Revista Médica del Hospital General de México Critical COVID-19. Pregnant women. Proinflammatory cytokines. |
| title | Profile of proinflammatory markers in pregnant women who died of severe COVID-19 |
| title_full | Profile of proinflammatory markers in pregnant women who died of severe COVID-19 |
| title_fullStr | Profile of proinflammatory markers in pregnant women who died of severe COVID-19 |
| title_full_unstemmed | Profile of proinflammatory markers in pregnant women who died of severe COVID-19 |
| title_short | Profile of proinflammatory markers in pregnant women who died of severe COVID-19 |
| title_sort | profile of proinflammatory markers in pregnant women who died of severe covid 19 |
| topic | Critical COVID-19. Pregnant women. Proinflammatory cytokines. |
| url | https://www.hospitalgeneral.mx/frame_eng.php?id=239 |
| work_keys_str_mv | AT pablobbautistagarcia profileofproinflammatorymarkersinpregnantwomenwhodiedofseverecovid19 AT marianabahenacampos profileofproinflammatorymarkersinpregnantwomenwhodiedofseverecovid19 AT dianahalcantararosas profileofproinflammatorymarkersinpregnantwomenwhodiedofseverecovid19 |