Generation of induced alveolar assembloids with functional alveolar-like macrophages

Generation of induced alveolar assembloids with functional alveolar-like macrophages

Abstract Within the human lung, interactions between alveolar epithelial cells and resident macrophages shape lung development and function in both health and disease. To study these processes, we develop a co-culture system combining human pluripotent stem cell-derived alveolar epithelial organoids...

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Bibliographic Details
Main Authors: Ji Su Kang, Youngsun Lee, Dayeon Gil, Min Jung Kim, Connor Wood, Vincent Delorme, Jeong Mi Lee, Kyong-Cheol Ko, Jung-Hyun Kim, Mi-Ok Lee
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58450-w
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