PfMORC protein regulates chromatin accessibility and transcriptional repression in the human malaria parasite, Plasmodium falciparum

PfMORC protein regulates chromatin accessibility and transcriptional repression in the human malaria parasite, Plasmodium falciparum

The environmental challenges the human malaria parasite, Plasmodium falciparum, faces during its progression into its various lifecycle stages warrant the use of effective and highly regulated access to chromatin for transcriptional regulation. Microrchidia (MORC) proteins have been implicated in DN...

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Bibliographic Details
Main Authors: Zeinab M Chahine, Mohit Gupta, Todd Lenz, Thomas Hollin, Steven Abel, Charles Banks, Anita Saraf, Jacques Prudhomme, Suhani Bhanvadia, Laurence A Florens, Karine G Le Roch
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-12-01
Series:eLife
Subjects:
malaria
epigenetic
chromatin
gene regulation
Online Access:https://elifesciences.org/articles/92499
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