Humanized Mouse Models for Immuno-Oncology Research: A Review and Implications in Lung Cancer Research

Humanized Mouse Models for Immuno-Oncology Research: A Review and Implications in Lung Cancer Research

Cancer immunotherapy has brought significant clinical benefits to patients with cancer, including those with lung cancer. Patient-derived tumor xenograft mouse models have become the preferred animal model for translational cancer research and preclinical studies. Given the unmet need for improved p...

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Bibliographic Details
Main Authors: Cheol-Kyu Park, MD, PhD, Maryam Khalil, BSc, Nhu-An Pham, PhD, Stephanie Wong, BSc, Dalam Ly, PhD, Adrian Sacher, MD, FRCPC, Ming-Sound Tsao, MD, FRCPC
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:JTO Clinical and Research Reports
Subjects:
Lung cancer
Immunotherapy
Humanized mouse models
Patient-derived xenograft
Online Access:http://www.sciencedirect.com/science/article/pii/S2666364324001516
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