Basal Ganglia Disease and Visuospatial Cognition: Are There Disease-Specific Impairments?
Visuospatial deficits in basal ganglia disease may be a non-specific function of the severity of dementia or they could reflect disease-specific impairments. To examine this question, Huntington (HD) patients, demented and non-demented Parkinson (PD) patients and healthy controls were examined with...
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| Format: | Article |
| Language: | English |
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Wiley
1997-01-01
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| Series: | Behavioural Neurology |
| Online Access: | http://dx.doi.org/10.3233/BEN-1997-102-304 |
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| _version_ | 1832560967754448896 |
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| author | Erich Mohr Jules J. Claus Pim Brouwers |
| author_facet | Erich Mohr Jules J. Claus Pim Brouwers |
| author_sort | Erich Mohr |
| collection | DOAJ |
| description | Visuospatial deficits in basal ganglia disease may be a non-specific function of the severity of dementia or they could reflect disease-specific impairments. To examine this question, Huntington (HD) patients, demented and non-demented Parkinson (PD) patients and healthy controls were examined with neuropsychological tests emphasising visuospatial abilities. Global intellectual function and general visuospatial cognition were less efficient in the two demented patient groups relative to both controls and non-demented PD patients and they did not differ significantly between non-demented Parkinsonians and controls nor between demented PD and HD patients. However, HD patients but not demented PD patients were impaired on a test of person-centred spatial judgement compared to non-demented subjects while demented PD patients scored significantly lower than HD patients on a test of field independence. Factor analysis yielded a factor reflecting general visuospatial processing capacity which discriminated between demented and non-demented PD patients but not between demented PD and HD patients. A unique factor associated with the manipulation of person-centred space discriminated between demented PD and HD patients. These results suggest general visuospatial processing is impaired as a non-specific function of dementia presence in HD and PD. Abnormalities in circumscribed aspects of visuospatial function, on the other hand, may differentiate between HD and PD, suggesting differential involvement of the basal ganglia in the respective illnesses. |
| format | Article |
| id | doaj-art-c0e2a5d10c8d49a7bddac9c47c080c32 |
| institution | Kabale University |
| issn | 0953-4180 1875-8584 |
| language | English |
| publishDate | 1997-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Behavioural Neurology |
| spelling | doaj-art-c0e2a5d10c8d49a7bddac9c47c080c322025-02-03T01:26:24ZengWileyBehavioural Neurology0953-41801875-85841997-01-01102-3677510.3233/BEN-1997-102-304Basal Ganglia Disease and Visuospatial Cognition: Are There Disease-Specific Impairments?Erich Mohr0Jules J. Claus1Pim Brouwers2Division of Neurology, University of Ottawa, Ottawa Civic Hospital and Elisabeth Bruyere Health Centre, Ottawa, CanadaDepartment of Neurology, Academic Medical Center, University of Amsterdam, The NetherlandsHIV and AIDS Malignancy, Division of Clinical Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USAVisuospatial deficits in basal ganglia disease may be a non-specific function of the severity of dementia or they could reflect disease-specific impairments. To examine this question, Huntington (HD) patients, demented and non-demented Parkinson (PD) patients and healthy controls were examined with neuropsychological tests emphasising visuospatial abilities. Global intellectual function and general visuospatial cognition were less efficient in the two demented patient groups relative to both controls and non-demented PD patients and they did not differ significantly between non-demented Parkinsonians and controls nor between demented PD and HD patients. However, HD patients but not demented PD patients were impaired on a test of person-centred spatial judgement compared to non-demented subjects while demented PD patients scored significantly lower than HD patients on a test of field independence. Factor analysis yielded a factor reflecting general visuospatial processing capacity which discriminated between demented and non-demented PD patients but not between demented PD and HD patients. A unique factor associated with the manipulation of person-centred space discriminated between demented PD and HD patients. These results suggest general visuospatial processing is impaired as a non-specific function of dementia presence in HD and PD. Abnormalities in circumscribed aspects of visuospatial function, on the other hand, may differentiate between HD and PD, suggesting differential involvement of the basal ganglia in the respective illnesses.http://dx.doi.org/10.3233/BEN-1997-102-304 |
| spellingShingle | Erich Mohr Jules J. Claus Pim Brouwers Basal Ganglia Disease and Visuospatial Cognition: Are There Disease-Specific Impairments? Behavioural Neurology |
| title | Basal Ganglia Disease and Visuospatial Cognition: Are There Disease-Specific Impairments? |
| title_full | Basal Ganglia Disease and Visuospatial Cognition: Are There Disease-Specific Impairments? |
| title_fullStr | Basal Ganglia Disease and Visuospatial Cognition: Are There Disease-Specific Impairments? |
| title_full_unstemmed | Basal Ganglia Disease and Visuospatial Cognition: Are There Disease-Specific Impairments? |
| title_short | Basal Ganglia Disease and Visuospatial Cognition: Are There Disease-Specific Impairments? |
| title_sort | basal ganglia disease and visuospatial cognition are there disease specific impairments |
| url | http://dx.doi.org/10.3233/BEN-1997-102-304 |
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