Coexistence of intracranial marginal zone B-cell lymphoma and meningioma: Case report and review of the literature

Synchronous presentation of multiple primary central nervous system tumors is extremely rare. Meningioma is the most commonly reported tumor in association with other intracranial neoplasms. Review of the literature revealed only 17 cases of meningiomas co-existing with intracranial lymphomas. A 44-...

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Main Authors: Ebru Cakir, Zubeyde Yildirim, Ulku Kucuk, Emel Ebru Pala, Ali Ozcan Binatli, Umit Bayol
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2014-09-01
Series:Indian Journal of Neurosurgery
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/2277-9167.146830
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author Ebru Cakir
Zubeyde Yildirim
Ulku Kucuk
Emel Ebru Pala
Ali Ozcan Binatli
Umit Bayol
author_facet Ebru Cakir
Zubeyde Yildirim
Ulku Kucuk
Emel Ebru Pala
Ali Ozcan Binatli
Umit Bayol
author_sort Ebru Cakir
collection DOAJ
description Synchronous presentation of multiple primary central nervous system tumors is extremely rare. Meningioma is the most commonly reported tumor in association with other intracranial neoplasms. Review of the literature revealed only 17 cases of meningiomas co-existing with intracranial lymphomas. A 44-year-old woman presented with headache and facial paresis. Magnetic resonance imaging revealed intracranial dural-epidural right frontal mass with tumor extension into the overlying calvarium. A right frontotemporal craniotomy and tumor resection was performed. Histopathologic examination showed a composite meningioma and marginal zone B-cell lymphoma. Radiographic, laboratory, and bone marrow examinations failed to reveal any evidence of systemic disease. Of the 17 lymphoma patients associated with meningioma, two were mucosa-associated lymphoid tissue type but both of these tumors were systemic metastases to intracranial meningiomas. Present report is the first case of a primary intracranial marginal zone B-cell lymphoma interdigitated with a fibroblastic type meningioma.
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publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
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series Indian Journal of Neurosurgery
spelling doaj-art-c0b710fcf6074c2c91ebb2117858a4d52025-08-20T03:05:14ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Neurosurgery2277-954X2277-91672014-09-01030315415710.4103/2277-9167.146830Coexistence of intracranial marginal zone B-cell lymphoma and meningioma: Case report and review of the literatureEbru CakirZubeyde YildirimUlku KucukEmel Ebru PalaAli Ozcan Binatli0Umit BayolNeurosurgery, Tepecik Education and Research HospitalSynchronous presentation of multiple primary central nervous system tumors is extremely rare. Meningioma is the most commonly reported tumor in association with other intracranial neoplasms. Review of the literature revealed only 17 cases of meningiomas co-existing with intracranial lymphomas. A 44-year-old woman presented with headache and facial paresis. Magnetic resonance imaging revealed intracranial dural-epidural right frontal mass with tumor extension into the overlying calvarium. A right frontotemporal craniotomy and tumor resection was performed. Histopathologic examination showed a composite meningioma and marginal zone B-cell lymphoma. Radiographic, laboratory, and bone marrow examinations failed to reveal any evidence of systemic disease. Of the 17 lymphoma patients associated with meningioma, two were mucosa-associated lymphoid tissue type but both of these tumors were systemic metastases to intracranial meningiomas. Present report is the first case of a primary intracranial marginal zone B-cell lymphoma interdigitated with a fibroblastic type meningioma.http://www.thieme-connect.de/DOI/DOI?10.4103/2277-9167.146830brain synchronous tumorslymphomameningioma
spellingShingle Ebru Cakir
Zubeyde Yildirim
Ulku Kucuk
Emel Ebru Pala
Ali Ozcan Binatli
Umit Bayol
Coexistence of intracranial marginal zone B-cell lymphoma and meningioma: Case report and review of the literature
Indian Journal of Neurosurgery
brain synchronous tumors
lymphoma
meningioma
title Coexistence of intracranial marginal zone B-cell lymphoma and meningioma: Case report and review of the literature
title_full Coexistence of intracranial marginal zone B-cell lymphoma and meningioma: Case report and review of the literature
title_fullStr Coexistence of intracranial marginal zone B-cell lymphoma and meningioma: Case report and review of the literature
title_full_unstemmed Coexistence of intracranial marginal zone B-cell lymphoma and meningioma: Case report and review of the literature
title_short Coexistence of intracranial marginal zone B-cell lymphoma and meningioma: Case report and review of the literature
title_sort coexistence of intracranial marginal zone b cell lymphoma and meningioma case report and review of the literature
topic brain synchronous tumors
lymphoma
meningioma
url http://www.thieme-connect.de/DOI/DOI?10.4103/2277-9167.146830
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