Comparing the effects of propolis extract mouthwash with Nystatin mouthwash on denture stomatitis
Background. Denture stomatitis is the most important clinical complication that is common in denture wearers. Candida albicans is the most important microorganism involved in the pathogenesis of this disease. Since the antifungal activity of propolis extract on Candida albicans has been proven in th...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | fas |
| Published: |
Tabriz University of Medical Sciences
2025-04-01
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| Series: | مجله پزشکی دانشگاه علوم پزشکی تبریز |
| Subjects: | |
| Online Access: | https://mj.tbzmed.ac.ir/PDF/mj-47-52.pdf |
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| Summary: | Background. Denture stomatitis is the most important clinical complication that is common in denture wearers. Candida albicans is the most important microorganism involved in the pathogenesis of this disease. Since the antifungal activity of propolis extract on Candida albicans has been proven in the laboratory, the aim of the study is to compare the mouthwash of propolis extract and nystatin in the treatment of denture stomatitis. Methods. In this study, thirty people with full removable dentures, suffering from type two denture stomatitis with symptoms of a wide erythematous area of the mucosa covered by the denture, participated. Propolis extract mouthwash was given to one group and nystatin mouthwash to the other group. The size of the erythema caused by denture stomatitis was taken before the start of mouthwash use, five, ten, fifteen and twenty days after the start of use, and the obtained data were analyzed by descriptive statistical methods and repeated analysis of variance, and P < 0.05 was considered significant. Results. There is a statistically significant difference between the average size of the erythema in the two groups under investigation at five and ten days after the start of use, which is greater in the nystatin group than the average in the propolis extract group, and at other evaluation times between the average There is no statistically significant difference in the size of the erythema in the two groups. Conclusion. Propolis extract mouthwash has the same effect as nystatin mouthwash in the treatment of denture stomatitis and due to its cheapness, ease of access, better taste and less side effects than nystatin, it is recommended for the treatment of fungal lesions including denture stomatitis. Practical Implications. Considering the benefits of propolis extract mouthwash compared to nystatin mouthwash, while having the same effects, the healthcare system should take measures to increase the consumption and prosperity of this mouthwash. |
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| ISSN: | 2783-2031 2783-204X |