Positive correlation between functional disability, excessive daytime sleepiness, and fatigue in relapsing-remitting multiple sclerosis
ABSTRACT Sleep disorders in patients with multiple sclerosis have various causes and interfere with daytime wakefulness. This study assessed the correlation between fatigue, excessive daytime sleepiness and level of disability. Method Retrospective review of medical records from patients with mult...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações
2016-06-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/pdf/anp/v74n6/0004-282X-anp-74-06-0433.pdf |
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| author | Douglas Martins Braga Gilmar Fernandes do Prado Denis Bernardi Bichueti Enedina Maria Lobato de Oliveira |
| author_facet | Douglas Martins Braga Gilmar Fernandes do Prado Denis Bernardi Bichueti Enedina Maria Lobato de Oliveira |
| author_sort | Douglas Martins Braga |
| collection | DOAJ |
| description | ABSTRACT Sleep disorders in patients with multiple sclerosis have various causes and interfere with daytime wakefulness. This study assessed the correlation between fatigue, excessive daytime sleepiness and level of disability. Method Retrospective review of medical records from patients with multiple sclerosis to collect data on severity of fatigue, disability, daytime sleepiness, and depression. From 912 medical records reviewed, 122 reported daytime sleepiness: 67% had relapsing remitting, 12% had primary progressive, and 21% had secondary progressive. Results In 95% of the patients with relapsing remitting who complained of daytime sleepiness and fatigue, association was found between these symptoms and neurological disability. Patients with relapsing remitting who complained of daytime sleepiness and fatigue also experienced depression (p = 0.001). No association between fatigue, excessive daytime sleepiness, depression, and disability was found in patients with progressive disease. Conclusion In relapsing remitting, there is correlation between functional disability, excessive daytime sleepiness and fatigue, a finding not confirmed in primary progressive and secondary progressive form. |
| format | Article |
| id | doaj-art-c0aa4e4fe58e432189be2294c5ef5daf |
| institution | DOAJ |
| issn | 1678-4227 |
| language | English |
| publishDate | 2016-06-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-c0aa4e4fe58e432189be2294c5ef5daf2025-08-20T03:05:13ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272016-06-0174643343810.1590/0004-282x20160069Positive correlation between functional disability, excessive daytime sleepiness, and fatigue in relapsing-remitting multiple sclerosisDouglas Martins BragaGilmar Fernandes do PradoDenis Bernardi BichuetiEnedina Maria Lobato de OliveiraABSTRACT Sleep disorders in patients with multiple sclerosis have various causes and interfere with daytime wakefulness. This study assessed the correlation between fatigue, excessive daytime sleepiness and level of disability. Method Retrospective review of medical records from patients with multiple sclerosis to collect data on severity of fatigue, disability, daytime sleepiness, and depression. From 912 medical records reviewed, 122 reported daytime sleepiness: 67% had relapsing remitting, 12% had primary progressive, and 21% had secondary progressive. Results In 95% of the patients with relapsing remitting who complained of daytime sleepiness and fatigue, association was found between these symptoms and neurological disability. Patients with relapsing remitting who complained of daytime sleepiness and fatigue also experienced depression (p = 0.001). No association between fatigue, excessive daytime sleepiness, depression, and disability was found in patients with progressive disease. Conclusion In relapsing remitting, there is correlation between functional disability, excessive daytime sleepiness and fatigue, a finding not confirmed in primary progressive and secondary progressive form.http://www.scielo.br/pdf/anp/v74n6/0004-282X-anp-74-06-0433.pdfmultiple sclerosisdisabled personsfatiguedisorders of excessive sonnolence |
| spellingShingle | Douglas Martins Braga Gilmar Fernandes do Prado Denis Bernardi Bichueti Enedina Maria Lobato de Oliveira Positive correlation between functional disability, excessive daytime sleepiness, and fatigue in relapsing-remitting multiple sclerosis Arquivos de Neuro-Psiquiatria multiple sclerosis disabled persons fatigue disorders of excessive sonnolence |
| title | Positive correlation between functional disability, excessive daytime sleepiness, and fatigue in relapsing-remitting multiple sclerosis |
| title_full | Positive correlation between functional disability, excessive daytime sleepiness, and fatigue in relapsing-remitting multiple sclerosis |
| title_fullStr | Positive correlation between functional disability, excessive daytime sleepiness, and fatigue in relapsing-remitting multiple sclerosis |
| title_full_unstemmed | Positive correlation between functional disability, excessive daytime sleepiness, and fatigue in relapsing-remitting multiple sclerosis |
| title_short | Positive correlation between functional disability, excessive daytime sleepiness, and fatigue in relapsing-remitting multiple sclerosis |
| title_sort | positive correlation between functional disability excessive daytime sleepiness and fatigue in relapsing remitting multiple sclerosis |
| topic | multiple sclerosis disabled persons fatigue disorders of excessive sonnolence |
| url | http://www.scielo.br/pdf/anp/v74n6/0004-282X-anp-74-06-0433.pdf |
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