Consequence of the tumor‐associated conversion to cyclin D1b

Consequence of the tumor‐associated conversion to cyclin D1b

Abstract Clinical evidence suggests that cyclin D1b, a variant of cyclin D1, is associated with tumor progression and poor outcome. However, the underlying molecular basis was unknown. Here, novel models were created to generate a genetic switch from cyclin D1 to cyclin D1b. Extensive analyses uncov...

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Bibliographic Details
Main Authors: Michael A Augello, Lisa D Berman‐Booty, Richard Carr, Akihiro Yoshida, Jeffry L Dean, Matthew J Schiewer, Felix Y Feng, Scott A Tomlins, Erhe Gao, Walter J Koch, Jeffrey L Benovic, John Alan Diehl, Karen E Knudsen
Format: Article
Language:English
Published: Springer Nature 2015-03-01
Series:EMBO Molecular Medicine
Subjects:
cell cycle
cyclin
cyclin D1b
PARP
Online Access:https://doi.org/10.15252/emmm.201404242
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