Effects of mini-dose esketamine–dexmedetomidine combination supplemented intravenous analgesia on postoperative sleep quality in elderly patients after total knee arthroplasty: a protocol of double-blind randomised trial

Introduction Postoperative sleep quality is generally impaired in elderly patients undergoing total knee arthroplasty. Decreased postoperative sleep quality seriously affects postoperative recovery. Both esketamine and dexmedetomidine have been individually demonstrated to have the potential to enha...

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Bibliographic Details
Main Authors: Xiaoyan Wang, Xiaoli Ji, Jinfeng Liu, Caicai Liu, Yanhua Luo
Format: Article
Language:English
Published: BMJ Publishing Group 2025-05-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/5/e098018.full
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