In vitro and in vivo vein assessment of a novel vein visualizing device to improve first-time peripheral venous access
Objective: Inserting needles into veins is fundamental to medical care with up to 90% of inpatients requiring a peripheral intravenous catheter/cannula (PIVC) during their stay. Yet 40%–50% of PIVC insertions fail on the first attempt. Here, we present an easy-to-use novel vein visualizing ultrasoun...
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| Format: | Article |
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Elsevier
2025-06-01
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| Series: | WFUMB Ultrasound Open |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949668325000072 |
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| author | Michael D. Liddelow Phuoc Hao Ho Cara A. Boyce Matthew D. Redknap Ellaby L. Hansen Nicholas M. Buckley Katherine Arenson Peter J. Carr Barry J. Doyle Nikhilesh Bappoo |
| author_facet | Michael D. Liddelow Phuoc Hao Ho Cara A. Boyce Matthew D. Redknap Ellaby L. Hansen Nicholas M. Buckley Katherine Arenson Peter J. Carr Barry J. Doyle Nikhilesh Bappoo |
| author_sort | Michael D. Liddelow |
| collection | DOAJ |
| description | Objective: Inserting needles into veins is fundamental to medical care with up to 90% of inpatients requiring a peripheral intravenous catheter/cannula (PIVC) during their stay. Yet 40%–50% of PIVC insertions fail on the first attempt. Here, we present an easy-to-use novel vein visualizing ultrasound prototype device and data from in vitro and in vivo performance. Methods: Locational accuracy was determined through phantom simulated forearm veins, across variations of vein diameter (3–5 mm), depth (10–20 mm), and velocity (10–100 mm/s). Usability studies were conducted on nine clinicians to establish effectiveness and ease of use of the proposed prototype assisted cannulation workflow. Sensitivity of the prototype was demonstrated by scanning 80 forearm veins across 40 healthy volunteers. Results: Our prototype's locational accuracy in simulated forearm veins is 0.21 mm ± 1.71 mm (s.d.) (97.7% agreement to the ground truth, p < .001). Usability studies found that 100% of users were able to handle the prototype in a sterile manner with minimal assistance. The sensitivity was excellent at finding veins (94%). In comparison, sensitivity of vein finding using landmark technique with torniquet (visible 46% and palpable 74%) were far inferior. Conclusion: Initial performance verification and validation studies presented suggest that the proposed ultrasound visualization method can simply and reliably help clinicians detect well-perfused veins at depth and visualize in the coronal view onboard the probe in alignment with the transducers. With improved ergonomics, the device has the potential to be an easy to use device for clinicians performing vascular access. |
| format | Article |
| id | doaj-art-c09a0f19b29e41c08217ec3737b0118e |
| institution | OA Journals |
| issn | 2949-6683 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | WFUMB Ultrasound Open |
| spelling | doaj-art-c09a0f19b29e41c08217ec3737b0118e2025-08-20T01:51:04ZengElsevierWFUMB Ultrasound Open2949-66832025-06-013110008510.1016/j.wfumbo.2025.100085In vitro and in vivo vein assessment of a novel vein visualizing device to improve first-time peripheral venous accessMichael D. Liddelow0Phuoc Hao Ho1Cara A. Boyce2Matthew D. Redknap3Ellaby L. Hansen4Nicholas M. Buckley5Katherine Arenson6Peter J. Carr7Barry J. Doyle8Nikhilesh Bappoo9VeinTech Pty Ltd, Perth, Western Australia, AustraliaVeinTech Pty Ltd, Perth, Western Australia, AustraliaVeinTech Pty Ltd, Perth, Western Australia, Australia; School of Engineering, The University of Western Australia, Perth, Western Australia, AustraliaVeinTech Pty Ltd, Perth, Western Australia, AustraliaVeinTech Pty Ltd, Perth, Western Australia, Australia; School of Engineering, The University of Western Australia, Perth, Western Australia, AustraliaVeinTech Pty Ltd, Perth, Western Australia, Australia; Telethon Kids Institute, Nedlands, Western Australia, Australia; School of Allied Health, Curtin University, Perth, Western Australia, AustraliaVeinTech Pty Ltd, Perth, Western Australia, Australia; Armadale Hospital, East Metropolitan Health Services, Western Australia, AustraliaSchool of Nursing and Midwifery, University of Galway, Galway, Ireland; Alliance for Vascular Access Teaching and Research Group, School of Nursing and Midwifery, Griffith University, Nathan, Queensland, AustraliaSchool of Engineering, The University of Western Australia, Perth, Western Australia, Australia; Vascular Engineering Laboratory, Harry Perkins Institute of Medical Research, QEII Medical Centre Nedlands and Centre for Medical Research, The University of Western Australia, Western Australia, AustraliaVeinTech Pty Ltd, Perth, Western Australia, Australia; School of Engineering, The University of Western Australia, Perth, Western Australia, Australia; Vascular Engineering Laboratory, Harry Perkins Institute of Medical Research, QEII Medical Centre Nedlands and Centre for Medical Research, The University of Western Australia, Western Australia, Australia; Corresponding author. VeinTech Pty Ltd, Perth, Western Australia, AustraliaObjective: Inserting needles into veins is fundamental to medical care with up to 90% of inpatients requiring a peripheral intravenous catheter/cannula (PIVC) during their stay. Yet 40%–50% of PIVC insertions fail on the first attempt. Here, we present an easy-to-use novel vein visualizing ultrasound prototype device and data from in vitro and in vivo performance. Methods: Locational accuracy was determined through phantom simulated forearm veins, across variations of vein diameter (3–5 mm), depth (10–20 mm), and velocity (10–100 mm/s). Usability studies were conducted on nine clinicians to establish effectiveness and ease of use of the proposed prototype assisted cannulation workflow. Sensitivity of the prototype was demonstrated by scanning 80 forearm veins across 40 healthy volunteers. Results: Our prototype's locational accuracy in simulated forearm veins is 0.21 mm ± 1.71 mm (s.d.) (97.7% agreement to the ground truth, p < .001). Usability studies found that 100% of users were able to handle the prototype in a sterile manner with minimal assistance. The sensitivity was excellent at finding veins (94%). In comparison, sensitivity of vein finding using landmark technique with torniquet (visible 46% and palpable 74%) were far inferior. Conclusion: Initial performance verification and validation studies presented suggest that the proposed ultrasound visualization method can simply and reliably help clinicians detect well-perfused veins at depth and visualize in the coronal view onboard the probe in alignment with the transducers. With improved ergonomics, the device has the potential to be an easy to use device for clinicians performing vascular access.http://www.sciencedirect.com/science/article/pii/S2949668325000072CannulationUltrasoundPortableVisualizationCoronalUsability |
| spellingShingle | Michael D. Liddelow Phuoc Hao Ho Cara A. Boyce Matthew D. Redknap Ellaby L. Hansen Nicholas M. Buckley Katherine Arenson Peter J. Carr Barry J. Doyle Nikhilesh Bappoo In vitro and in vivo vein assessment of a novel vein visualizing device to improve first-time peripheral venous access WFUMB Ultrasound Open Cannulation Ultrasound Portable Visualization Coronal Usability |
| title | In vitro and in vivo vein assessment of a novel vein visualizing device to improve first-time peripheral venous access |
| title_full | In vitro and in vivo vein assessment of a novel vein visualizing device to improve first-time peripheral venous access |
| title_fullStr | In vitro and in vivo vein assessment of a novel vein visualizing device to improve first-time peripheral venous access |
| title_full_unstemmed | In vitro and in vivo vein assessment of a novel vein visualizing device to improve first-time peripheral venous access |
| title_short | In vitro and in vivo vein assessment of a novel vein visualizing device to improve first-time peripheral venous access |
| title_sort | in vitro and in vivo vein assessment of a novel vein visualizing device to improve first time peripheral venous access |
| topic | Cannulation Ultrasound Portable Visualization Coronal Usability |
| url | http://www.sciencedirect.com/science/article/pii/S2949668325000072 |
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