Arterial hypertension with stroke risk: clinical features, circadian blood pressure profiles, angiotensin II antagonist treatment
Aim. To investigate arterial hypertension (AH) clinical features in patients who suffered stroke (S) in previous 12 months. Material and methods. Prevalence of various risk factors (RF), target organ damage and associated pathology, was compared in two groups: Group I – 500 S-free AH patients, mean...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2005-06-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/965 |
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| author | V. B. Simonenko A. Ya. Fisun E. A. Shirokov V. F. Zhukov V. A. Igonin I. S. Denishchuk A. V. Kuroedov Yu. V. Ovchinnikov M. V. Brizhan |
| author_facet | V. B. Simonenko A. Ya. Fisun E. A. Shirokov V. F. Zhukov V. A. Igonin I. S. Denishchuk A. V. Kuroedov Yu. V. Ovchinnikov M. V. Brizhan |
| author_sort | V. B. Simonenko |
| collection | DOAJ |
| description | Aim. To investigate arterial hypertension (AH) clinical features in patients who suffered stroke (S) in previous 12 months. Material and methods. Prevalence of various risk factors (RF), target organ damage and associated pathology, was compared in two groups: Group I – 500 S-free AH patients, mean age 64.8±6.2 years; Group II - 467 AH patients with S, mean age 66.2±4.3 years. 24-hour blood pressure monitoring, brachiocephalic artery duplex scanning, and echocardiography were preformed in all participants. Results. In pre-S period, a syndrome of “poor prognosis” could be identified, that included some clinical and instrumental symptoms of aggressive RF influence and cardiovascular remodeling. In AH patients with high S risk, circadian BP profiles were disturbed, with increased prevalence of non-dippers, over-dippers, and night-peakers. Conclusion. Long-term antihypertensive therapy with eprosartan in AH patients with or without S, demonstrated multiple beneficial effects: target BP level achievement, and circadian BP profile normalization. |
| format | Article |
| id | doaj-art-c0976fa648f747659bbfafc7ea5b2096 |
| institution | DOAJ |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2005-06-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-c0976fa648f747659bbfafc7ea5b20962025-08-20T02:55:48Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252005-06-0143, ч.I2934679Arterial hypertension with stroke risk: clinical features, circadian blood pressure profiles, angiotensin II antagonist treatmentV. B. Simonenko0A. Ya. Fisun1E. A. Shirokov2V. F. Zhukov3V. A. Igonin4I. S. Denishchuk5A. V. Kuroedov6Yu. V. Ovchinnikov7M. V. Brizhan8P.V. Mandryka Second Central Military Clinical Hospital; State Institute for Continuous Medical Education, Ministry of Education of the Russian Federation, MoscowP.V. Mandryka Second Central Military Clinical Hospital; State Institute for Continuous Medical Education, Ministry of Education of the Russian Federation, MoscowP.V. Mandryka Second Central Military Clinical HospitalP.V. Mandryka Second Central Military Clinical HospitalState Institute for Continuous Medical Education, Ministry of Education of the Russian Federation, MoscowP.V. Mandryka Second Central Military Clinical Hospital; State Institute for Continuous Medical Education, Ministry of Education of the Russian Federation, MoscowP.V. Mandryka Second Central Military Clinical HospitalP.V. Mandryka Second Central Military Clinical Hospital; State Institute for Continuous Medical Education, Ministry of Education of the Russian Federation, MoscowState Institute for Continuous Medical Education, Ministry of Education of the Russian Federation, MoscowAim. To investigate arterial hypertension (AH) clinical features in patients who suffered stroke (S) in previous 12 months. Material and methods. Prevalence of various risk factors (RF), target organ damage and associated pathology, was compared in two groups: Group I – 500 S-free AH patients, mean age 64.8±6.2 years; Group II - 467 AH patients with S, mean age 66.2±4.3 years. 24-hour blood pressure monitoring, brachiocephalic artery duplex scanning, and echocardiography were preformed in all participants. Results. In pre-S period, a syndrome of “poor prognosis” could be identified, that included some clinical and instrumental symptoms of aggressive RF influence and cardiovascular remodeling. In AH patients with high S risk, circadian BP profiles were disturbed, with increased prevalence of non-dippers, over-dippers, and night-peakers. Conclusion. Long-term antihypertensive therapy with eprosartan in AH patients with or without S, demonstrated multiple beneficial effects: target BP level achievement, and circadian BP profile normalization.https://cardiovascular.elpub.ru/jour/article/view/965arterial hypertensionstroke24-hour blood pressure monitoringeprosartan |
| spellingShingle | V. B. Simonenko A. Ya. Fisun E. A. Shirokov V. F. Zhukov V. A. Igonin I. S. Denishchuk A. V. Kuroedov Yu. V. Ovchinnikov M. V. Brizhan Arterial hypertension with stroke risk: clinical features, circadian blood pressure profiles, angiotensin II antagonist treatment Кардиоваскулярная терапия и профилактика arterial hypertension stroke 24-hour blood pressure monitoring eprosartan |
| title | Arterial hypertension with stroke risk: clinical features, circadian blood pressure profiles, angiotensin II antagonist treatment |
| title_full | Arterial hypertension with stroke risk: clinical features, circadian blood pressure profiles, angiotensin II antagonist treatment |
| title_fullStr | Arterial hypertension with stroke risk: clinical features, circadian blood pressure profiles, angiotensin II antagonist treatment |
| title_full_unstemmed | Arterial hypertension with stroke risk: clinical features, circadian blood pressure profiles, angiotensin II antagonist treatment |
| title_short | Arterial hypertension with stroke risk: clinical features, circadian blood pressure profiles, angiotensin II antagonist treatment |
| title_sort | arterial hypertension with stroke risk clinical features circadian blood pressure profiles angiotensin ii antagonist treatment |
| topic | arterial hypertension stroke 24-hour blood pressure monitoring eprosartan |
| url | https://cardiovascular.elpub.ru/jour/article/view/965 |
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