Correlation of Triglyceride-Rich Lipoprotein Cholesterol and Diabetes Mellitus in Stroke Patients
Background. Previous studies have revealed that triglyceride-rich lipoprotein cholesterol (TRL-c) is closely related to diabetes mellitus (DM) in hypertensive patients. However, this relationship in stroke patients has not been reported. The aims of this study are to investigate the relationship bet...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2022/7506767 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850175810592309248 |
|---|---|
| author | Ruiqing Luo Huifang Jiang Tao Wang Yanfang Xu Xueliang Qi |
| author_facet | Ruiqing Luo Huifang Jiang Tao Wang Yanfang Xu Xueliang Qi |
| author_sort | Ruiqing Luo |
| collection | DOAJ |
| description | Background. Previous studies have revealed that triglyceride-rich lipoprotein cholesterol (TRL-c) is closely related to diabetes mellitus (DM) in hypertensive patients. However, this relationship in stroke patients has not been reported. The aims of this study are to investigate the relationship between TRL-c and diabetes in adult Chinese stroke. Methods. Patients with stroke treated in the Department of Neurology of the Second Affiliated Hospital of Nanchang University from January 2019 to January 2021 were selected. TRL-c was calculated from total cholesterol minus (high-density and low-density lipoprotein). DM was diagnosed based on previous medical history (diagnosed by secondary hospitals or above) and/or current use of hypoglycemic drugs and/or intravenous blood glucose measurement (fasting blood glucose ≥7.0 mmol/L or nonfasting blood glucose > 11.1 mmol/L). The relationship between the TRL-c and DM was determined using multivariate logistic regression, smoothing curve fitting (penalized spline method), and subgroup analysis. Results. A total of 890 patients with stroke (age, 66.1 ± 11.8 years) were enrolled, including 329 females. Multivariate logistic regression analysis demonstrated that TRL-c had a positive association with DM (OR 1.88; 95% CI: 1.22 to 2.89). Strong linear associations of TRL-c with DM were confirmed by restricted cubic spline analysis. And the association between TRL-c and DM was consistent in the different subgroups. Conclusion. Positive associations were found between TRL-c and DM in patients with stroke. |
| format | Article |
| id | doaj-art-c0953db0e29b469293c26fb660de31df |
| institution | OA Journals |
| issn | 1687-8345 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-c0953db0e29b469293c26fb660de31df2025-08-20T02:19:22ZengWileyInternational Journal of Endocrinology1687-83452022-01-01202210.1155/2022/7506767Correlation of Triglyceride-Rich Lipoprotein Cholesterol and Diabetes Mellitus in Stroke PatientsRuiqing Luo0Huifang Jiang1Tao Wang2Yanfang Xu3Xueliang Qi4Department of NeurologyDepartment of Medical RecordCenter for Prevention and Treatment of Cardiovascular DiseasesDepartment of NeurologyDepartment of NeurologyBackground. Previous studies have revealed that triglyceride-rich lipoprotein cholesterol (TRL-c) is closely related to diabetes mellitus (DM) in hypertensive patients. However, this relationship in stroke patients has not been reported. The aims of this study are to investigate the relationship between TRL-c and diabetes in adult Chinese stroke. Methods. Patients with stroke treated in the Department of Neurology of the Second Affiliated Hospital of Nanchang University from January 2019 to January 2021 were selected. TRL-c was calculated from total cholesterol minus (high-density and low-density lipoprotein). DM was diagnosed based on previous medical history (diagnosed by secondary hospitals or above) and/or current use of hypoglycemic drugs and/or intravenous blood glucose measurement (fasting blood glucose ≥7.0 mmol/L or nonfasting blood glucose > 11.1 mmol/L). The relationship between the TRL-c and DM was determined using multivariate logistic regression, smoothing curve fitting (penalized spline method), and subgroup analysis. Results. A total of 890 patients with stroke (age, 66.1 ± 11.8 years) were enrolled, including 329 females. Multivariate logistic regression analysis demonstrated that TRL-c had a positive association with DM (OR 1.88; 95% CI: 1.22 to 2.89). Strong linear associations of TRL-c with DM were confirmed by restricted cubic spline analysis. And the association between TRL-c and DM was consistent in the different subgroups. Conclusion. Positive associations were found between TRL-c and DM in patients with stroke.http://dx.doi.org/10.1155/2022/7506767 |
| spellingShingle | Ruiqing Luo Huifang Jiang Tao Wang Yanfang Xu Xueliang Qi Correlation of Triglyceride-Rich Lipoprotein Cholesterol and Diabetes Mellitus in Stroke Patients International Journal of Endocrinology |
| title | Correlation of Triglyceride-Rich Lipoprotein Cholesterol and Diabetes Mellitus in Stroke Patients |
| title_full | Correlation of Triglyceride-Rich Lipoprotein Cholesterol and Diabetes Mellitus in Stroke Patients |
| title_fullStr | Correlation of Triglyceride-Rich Lipoprotein Cholesterol and Diabetes Mellitus in Stroke Patients |
| title_full_unstemmed | Correlation of Triglyceride-Rich Lipoprotein Cholesterol and Diabetes Mellitus in Stroke Patients |
| title_short | Correlation of Triglyceride-Rich Lipoprotein Cholesterol and Diabetes Mellitus in Stroke Patients |
| title_sort | correlation of triglyceride rich lipoprotein cholesterol and diabetes mellitus in stroke patients |
| url | http://dx.doi.org/10.1155/2022/7506767 |
| work_keys_str_mv | AT ruiqingluo correlationoftriglyceriderichlipoproteincholesterolanddiabetesmellitusinstrokepatients AT huifangjiang correlationoftriglyceriderichlipoproteincholesterolanddiabetesmellitusinstrokepatients AT taowang correlationoftriglyceriderichlipoproteincholesterolanddiabetesmellitusinstrokepatients AT yanfangxu correlationoftriglyceriderichlipoproteincholesterolanddiabetesmellitusinstrokepatients AT xueliangqi correlationoftriglyceriderichlipoproteincholesterolanddiabetesmellitusinstrokepatients |