Vortioxetine exhibits anti-glioblastoma activity via the PI3K-Akt signaling pathway

Vortioxetine exhibits anti-glioblastoma activity via the PI3K-Akt signaling pathway

Objective(s): Glioblastoma multiforme (GBM) presents a significant challenge in oncology due to its highly aggressive nature and inherent resistance to conventional therapeutic interventions. Vortioxetine, a novel antidepressant, exhibits anticancer abilities and can traverse the blood-brain barrier...

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Bibliographic Details
Main Authors:	Huan-Qi Zhang, Dao-Ming Zhang, Zhi-Zhen Huang, Jing Cheng, Chong Zhang, Neng-Ming Lin, Yang-Ling Li
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2025-04-01
Series:	Iranian Journal of Basic Medical Sciences
Subjects:	akt apoptosis autophagy gbm pi3k proliferation vortioxetine
Online Access:	https://ijbms.mums.ac.ir/article_25513_56423699efec3112603c93005c6f852e.pdf
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