The molecular mechanism of the protective effect of tianeptine against ovarian ischemia-reperfusion injury

The molecular mechanism of the protective effect of tianeptine against ovarian ischemia-reperfusion injury

Abstract Torsion of the ovary is a gynecologic emergency that occurs when the ovary and fallopian tube rotate around the infundibulopelvic ligament, causing ischemic changes in the adnexa. Tianeptine is an atypical antidepressant that has been shown to be effective in treatment-resistant depression...

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Bibliographic Details
Main Authors: Betul Kalkan, Bulent Yavuzer, Aydin Aliyev, Osman Kagan Cakir, Fusun Gozen, Ali Sefa Mendil, Taha Abdulkadir Coban, Halis Suleyman
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
8-OHdG
Ischemia-reperfusion injury
Ovary
Rats
Tianeptine
Online Access:https://doi.org/10.1038/s41598-025-13875-7
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