Efficacy, safety, and economic evaluation of Ojeok-san plus Saengmaek-san for gastroesophageal reflux-induced chronic cough: Protocol for a randomized, double-blind, placebo-controlled, parallel, multicenter, investigator-initiated clinical trial.

Efficacy, safety, and economic evaluation of Ojeok-san plus Saengmaek-san for gastroesophageal reflux-induced chronic cough: Protocol for a randomized, double-blind, placebo-controlled, parallel, multicenter, investigator-initiated clinical trial.

<h4>Introduction</h4>Gastroesophageal reflux-induced chronic cough (GERC) is a common extraesophageal manifestation of gastroesophageal reflux disease (GERD). However, the mechanisms underlying GERC remain unclear, and current treatments with anti-reflux drugs do not provide significant...

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Main Authors: Yee Ran Lyu, O-Jin Kwon, Ae-Ran Kim, Min Ji Kim, Yoon Jae Lee, Kwan-Il Kim, Jae-Woo Park, Seok-Jae Ko, Yang-Chun Park, Jun-Yong Choi, Tae-Yong Park, Jun-Hwan Lee, Beom-Joon Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0325786
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