Subacute Sclerosing Panencephalitis in a Toddler: Changing Epidemiological Trends
Subacute sclerosing panencephalitis (SSPE) is a devastating “slow virus” brain disease resulting from persistent measles virus infection of neurons. The age at presentation is usually 8 to 11 years with onset usually occurring 2–10 years after measles infection. We report a 2-and-half-year-old boy w...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2013/341462 |
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| author | Roosy Aulakh Abhimanyu Tiwari |
| author_facet | Roosy Aulakh Abhimanyu Tiwari |
| author_sort | Roosy Aulakh |
| collection | DOAJ |
| description | Subacute sclerosing panencephalitis (SSPE) is a devastating “slow virus” brain disease resulting from persistent measles virus infection of neurons. The age at presentation is usually 8 to 11 years with onset usually occurring 2–10 years after measles infection. We report a 2-and-half-year-old boy who presented with progressively increasing myoclonic jerks and subtle cognitive decline. He was diagnosed as a case of SSPE based on clinical features, typical electroencephalographic finding, and elevated cerebrospinal fluid/serum measles antibody titers. He had measles 4 months prior to onset of symptoms. This case along with review of recently published reports suggests progressively decreasing latency period between measles infection and onset of symptoms observed in cases with SSPE. Clinical implication would mean investigating for SSPE even in infants or toddlers with compatible clinical features and recent history of measles infection. |
| format | Article |
| id | doaj-art-c079a9a146ea43adb68c1dd32cacb1b1 |
| institution | DOAJ |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-c079a9a146ea43adb68c1dd32cacb1b12025-08-20T03:23:23ZengWileyCase Reports in Pediatrics2090-68032090-68112013-01-01201310.1155/2013/341462341462Subacute Sclerosing Panencephalitis in a Toddler: Changing Epidemiological TrendsRoosy Aulakh0Abhimanyu Tiwari1Division of Pediatric Neurology, Department of Pediatrics, Government Medical College & Hospital, Chandigarh 160030, IndiaDepartment of Pediatrics, Government Medical College & Hospital, Chandigarh 160030, IndiaSubacute sclerosing panencephalitis (SSPE) is a devastating “slow virus” brain disease resulting from persistent measles virus infection of neurons. The age at presentation is usually 8 to 11 years with onset usually occurring 2–10 years after measles infection. We report a 2-and-half-year-old boy who presented with progressively increasing myoclonic jerks and subtle cognitive decline. He was diagnosed as a case of SSPE based on clinical features, typical electroencephalographic finding, and elevated cerebrospinal fluid/serum measles antibody titers. He had measles 4 months prior to onset of symptoms. This case along with review of recently published reports suggests progressively decreasing latency period between measles infection and onset of symptoms observed in cases with SSPE. Clinical implication would mean investigating for SSPE even in infants or toddlers with compatible clinical features and recent history of measles infection.http://dx.doi.org/10.1155/2013/341462 |
| spellingShingle | Roosy Aulakh Abhimanyu Tiwari Subacute Sclerosing Panencephalitis in a Toddler: Changing Epidemiological Trends Case Reports in Pediatrics |
| title | Subacute Sclerosing Panencephalitis in a Toddler: Changing Epidemiological Trends |
| title_full | Subacute Sclerosing Panencephalitis in a Toddler: Changing Epidemiological Trends |
| title_fullStr | Subacute Sclerosing Panencephalitis in a Toddler: Changing Epidemiological Trends |
| title_full_unstemmed | Subacute Sclerosing Panencephalitis in a Toddler: Changing Epidemiological Trends |
| title_short | Subacute Sclerosing Panencephalitis in a Toddler: Changing Epidemiological Trends |
| title_sort | subacute sclerosing panencephalitis in a toddler changing epidemiological trends |
| url | http://dx.doi.org/10.1155/2013/341462 |
| work_keys_str_mv | AT roosyaulakh subacutesclerosingpanencephalitisinatoddlerchangingepidemiologicaltrends AT abhimanyutiwari subacutesclerosingpanencephalitisinatoddlerchangingepidemiologicaltrends |