Integrating artificial intelligence with miniature mass spectrometry

Miniature mass spectrometers are increasingly being employed in various analytical fields due to their portability and low cost. Unlike lab-scale mass spectrometers, miniature mass spectrometers typically operate in environments that demand more automated analytical processes for on-site, real-time...

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Main Authors: Jiayi Wang, Lingyan Liu, Ting Jiang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Green Analytical Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772577425000771
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author Jiayi Wang
Lingyan Liu
Ting Jiang
author_facet Jiayi Wang
Lingyan Liu
Ting Jiang
author_sort Jiayi Wang
collection DOAJ
description Miniature mass spectrometers are increasingly being employed in various analytical fields due to their portability and low cost. Unlike lab-scale mass spectrometers, miniature mass spectrometers typically operate in environments that demand more automated analytical processes for on-site, real-time analysis. With the successful application of AI across different industries, researchers have started to integrate AI techniques into miniature mass spectrometry to enhance its capabilities. In this review, we provide an overview of the recent advancements in the intelligence of miniature mass spectrometers, focusing on intelligent sample identification and AI methods that enhance the instruments’ performance. These AI methods have not only improved the accuracy and efficiency of analysis but have also expanded the applications of miniature mass spectrometry to critical areas such as food safety, agricultural disease detection, and environmental monitoring. Moreover, we discuss the current challenges in advancing the intelligence of miniature mass spectrometers and explore the complexities involved in integrating AI with these devices. Finally, we offer our insights into future directions and potential solutions for overcoming these challenges.
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series Green Analytical Chemistry
spelling doaj-art-c075aeb15f0b40b0a24e47d08468cc282025-08-20T03:53:56ZengElsevierGreen Analytical Chemistry2772-57742025-06-011310028110.1016/j.greeac.2025.100281Integrating artificial intelligence with miniature mass spectrometryJiayi Wang0Lingyan Liu1Ting Jiang2School of Medical Technology, Beijing Institute of Technology, Beijing 100081, ChinaSchool of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China; Corresponding author at: School of Pharmaceutical Sciences, Capital Medical University, Haidian, Beijing 100069, China.School of Medical Technology, Beijing Institute of Technology, Beijing 100081, China; Corresponding author at: School of Medical Technology, Beijing Institute of Technology, Haidian, Beijing 100081, China.Miniature mass spectrometers are increasingly being employed in various analytical fields due to their portability and low cost. Unlike lab-scale mass spectrometers, miniature mass spectrometers typically operate in environments that demand more automated analytical processes for on-site, real-time analysis. With the successful application of AI across different industries, researchers have started to integrate AI techniques into miniature mass spectrometry to enhance its capabilities. In this review, we provide an overview of the recent advancements in the intelligence of miniature mass spectrometers, focusing on intelligent sample identification and AI methods that enhance the instruments’ performance. These AI methods have not only improved the accuracy and efficiency of analysis but have also expanded the applications of miniature mass spectrometry to critical areas such as food safety, agricultural disease detection, and environmental monitoring. Moreover, we discuss the current challenges in advancing the intelligence of miniature mass spectrometers and explore the complexities involved in integrating AI with these devices. Finally, we offer our insights into future directions and potential solutions for overcoming these challenges.http://www.sciencedirect.com/science/article/pii/S2772577425000771Artificial intelligenceMiniature mass spectrometry
spellingShingle Jiayi Wang
Lingyan Liu
Ting Jiang
Integrating artificial intelligence with miniature mass spectrometry
Green Analytical Chemistry
Artificial intelligence
Miniature mass spectrometry
title Integrating artificial intelligence with miniature mass spectrometry
title_full Integrating artificial intelligence with miniature mass spectrometry
title_fullStr Integrating artificial intelligence with miniature mass spectrometry
title_full_unstemmed Integrating artificial intelligence with miniature mass spectrometry
title_short Integrating artificial intelligence with miniature mass spectrometry
title_sort integrating artificial intelligence with miniature mass spectrometry
topic Artificial intelligence
Miniature mass spectrometry
url http://www.sciencedirect.com/science/article/pii/S2772577425000771
work_keys_str_mv AT jiayiwang integratingartificialintelligencewithminiaturemassspectrometry
AT lingyanliu integratingartificialintelligencewithminiaturemassspectrometry
AT tingjiang integratingartificialintelligencewithminiaturemassspectrometry