Clinical and immunological features and treatment of myasthenia gravis in the elderly (review)
A literature review on the peculiarities of the diagnosis, course and treatment of myasthenia gravis in the elderly has been done. Despite the fact that myasthenia gravis is a disease of the young and middle-aged, in recent years, several authors observe an increased incidence among the elderly. A p...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2019-04-01
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| Series: | Нервно-мышечные болезни |
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| Online Access: | https://nmb.abvpress.ru/jour/article/view/166 |
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| author | T. M. Alekseeva V. D. Kosachev A. N. Khalmurzina |
| author_facet | T. M. Alekseeva V. D. Kosachev A. N. Khalmurzina |
| author_sort | T. M. Alekseeva |
| collection | DOAJ |
| description | A literature review on the peculiarities of the diagnosis, course and treatment of myasthenia gravis in the elderly has been done. Despite the fact that myasthenia gravis is a disease of the young and middle-aged, in recent years, several authors observe an increased incidence among the elderly. A proper diagnosis in this age group tend to cause difficulties, and concomitant diseases complicate the choice of therapeutic approach which includes: acetylcholinesterase inhibitors, steroids, immunosuppressants, intravenous immunoglobulins and plasmapheresis. Thymectomy in older age groups, except for the presence of thymoma, due to side effects and the lack of a strong evidence base, is not widely held. The question of the effectiveness and optimal therapeutic approach of myasthenia gravis in elderly patients is still not fully resolved. |
| format | Article |
| id | doaj-art-c0751f5347494a95bba51b08080f7298 |
| institution | Kabale University |
| issn | 2222-8721 2413-0443 |
| language | Russian |
| publishDate | 2019-04-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Нервно-мышечные болезни |
| spelling | doaj-art-c0751f5347494a95bba51b08080f72982025-08-20T03:38:15ZrusABV-pressНервно-мышечные болезни2222-87212413-04432019-04-0163101610.17650/2222-8721-2016-6-3-10-16144Clinical and immunological features and treatment of myasthenia gravis in the elderly (review)T. M. Alekseeva0V. D. Kosachev1A. N. Khalmurzina2I.I. Mechnikov North-Western State Medical University, Ministry of Health of RussiaI.I. Mechnikov North-Western State Medical University, Ministry of Health of RussiaI.I. Mechnikov North-Western State Medical University, Ministry of Health of RussiaA literature review on the peculiarities of the diagnosis, course and treatment of myasthenia gravis in the elderly has been done. Despite the fact that myasthenia gravis is a disease of the young and middle-aged, in recent years, several authors observe an increased incidence among the elderly. A proper diagnosis in this age group tend to cause difficulties, and concomitant diseases complicate the choice of therapeutic approach which includes: acetylcholinesterase inhibitors, steroids, immunosuppressants, intravenous immunoglobulins and plasmapheresis. Thymectomy in older age groups, except for the presence of thymoma, due to side effects and the lack of a strong evidence base, is not widely held. The question of the effectiveness and optimal therapeutic approach of myasthenia gravis in elderly patients is still not fully resolved.https://nmb.abvpress.ru/jour/article/view/166myasthenia graviselderlyacetylcholinesterase inhibitorsthymomathymectomyintravenous immunoglobulinsimmunosuppressive therapymyasthenic crisis |
| spellingShingle | T. M. Alekseeva V. D. Kosachev A. N. Khalmurzina Clinical and immunological features and treatment of myasthenia gravis in the elderly (review) Нервно-мышечные болезни myasthenia gravis elderly acetylcholinesterase inhibitors thymoma thymectomy intravenous immunoglobulins immunosuppressive therapy myasthenic crisis |
| title | Clinical and immunological features and treatment of myasthenia gravis in the elderly (review) |
| title_full | Clinical and immunological features and treatment of myasthenia gravis in the elderly (review) |
| title_fullStr | Clinical and immunological features and treatment of myasthenia gravis in the elderly (review) |
| title_full_unstemmed | Clinical and immunological features and treatment of myasthenia gravis in the elderly (review) |
| title_short | Clinical and immunological features and treatment of myasthenia gravis in the elderly (review) |
| title_sort | clinical and immunological features and treatment of myasthenia gravis in the elderly review |
| topic | myasthenia gravis elderly acetylcholinesterase inhibitors thymoma thymectomy intravenous immunoglobulins immunosuppressive therapy myasthenic crisis |
| url | https://nmb.abvpress.ru/jour/article/view/166 |
| work_keys_str_mv | AT tmalekseeva clinicalandimmunologicalfeaturesandtreatmentofmyastheniagravisintheelderlyreview AT vdkosachev clinicalandimmunologicalfeaturesandtreatmentofmyastheniagravisintheelderlyreview AT ankhalmurzina clinicalandimmunologicalfeaturesandtreatmentofmyastheniagravisintheelderlyreview |