Agent-based modeling of macrophage-fibroblast interactions in the immune response to biomaterials.

Agent-based modeling of macrophage-fibroblast interactions in the immune response to biomaterials.

Foreign body reaction (FBR) denotes the reaction to the implantation of a biomaterial into the body. It triggers cascades of responses in the tissue and involves different cell types including, among others, macrophages, fibroblasts and endothelial cells. Macrophages regulate the inflammatory and he...

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Bibliographic Details
Main Authors: Jennifer Riccio, Luca Presotto, Shir Bahiri, Liad Doniza, Donato Inverso, Laura Sironi, Uri Nevo, Giuseppe Chirico
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0329186
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