Real-Time fMRI Neurofeedback Modulation of Dopaminergic Midbrain Activity in Young Adults With Elevated Internet Gaming Disorder Risk: Randomized Controlled Trial
This study provides preliminary evidence for real-time functional magnetic resonance imaging neurofeedback (rt-fMRI NF) as a potential intervention approach for internet gaming disorder (IGD). In a preregistered, randomized, single-blind trial, young individuals with elevated IGD risk wer...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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JMIR Publications
2025-01-01
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| Series: | Journal of Medical Internet Research |
| Online Access: | https://www.jmir.org/2025/1/e64687 |
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| author | Anqi Gu Cheng Lam Chan Xiaolei Xu Joseph P Dexter Benjamin Becker Zhiying Zhao |
| author_facet | Anqi Gu Cheng Lam Chan Xiaolei Xu Joseph P Dexter Benjamin Becker Zhiying Zhao |
| author_sort | Anqi Gu |
| collection | DOAJ |
| description |
This study provides preliminary evidence for real-time functional magnetic resonance imaging neurofeedback (rt-fMRI NF) as a potential intervention approach for internet gaming disorder (IGD). In a preregistered, randomized, single-blind trial, young individuals with elevated IGD risk were trained to downregulate gaming addiction–related brain activity. We show that, after 2 sessions of neurofeedback training, participants successfully downregulated their brain responses to gaming cues, suggesting the therapeutic potential of rt-fMRI NF for IGD (Trial Registration: ClinicalTrials.gov NCT06063642; https://clinicaltrials.gov/study/NCT06063642). |
| format | Article |
| id | doaj-art-c06e0a61fc4a4f079a6f8210a130e18c |
| institution | Kabale University |
| issn | 1438-8871 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | JMIR Publications |
| record_format | Article |
| series | Journal of Medical Internet Research |
| spelling | doaj-art-c06e0a61fc4a4f079a6f8210a130e18c2025-01-29T18:00:52ZengJMIR PublicationsJournal of Medical Internet Research1438-88712025-01-0127e6468710.2196/64687Real-Time fMRI Neurofeedback Modulation of Dopaminergic Midbrain Activity in Young Adults With Elevated Internet Gaming Disorder Risk: Randomized Controlled TrialAnqi Guhttps://orcid.org/0009-0007-5771-330XCheng Lam Chanhttps://orcid.org/0009-0006-4430-4577Xiaolei Xuhttps://orcid.org/0000-0003-3817-0411Joseph P Dexterhttps://orcid.org/0000-0001-8524-5792Benjamin Beckerhttps://orcid.org/0000-0002-9014-9671Zhiying Zhaohttps://orcid.org/0000-0002-0369-1308 This study provides preliminary evidence for real-time functional magnetic resonance imaging neurofeedback (rt-fMRI NF) as a potential intervention approach for internet gaming disorder (IGD). In a preregistered, randomized, single-blind trial, young individuals with elevated IGD risk were trained to downregulate gaming addiction–related brain activity. We show that, after 2 sessions of neurofeedback training, participants successfully downregulated their brain responses to gaming cues, suggesting the therapeutic potential of rt-fMRI NF for IGD (Trial Registration: ClinicalTrials.gov NCT06063642; https://clinicaltrials.gov/study/NCT06063642).https://www.jmir.org/2025/1/e64687 |
| spellingShingle | Anqi Gu Cheng Lam Chan Xiaolei Xu Joseph P Dexter Benjamin Becker Zhiying Zhao Real-Time fMRI Neurofeedback Modulation of Dopaminergic Midbrain Activity in Young Adults With Elevated Internet Gaming Disorder Risk: Randomized Controlled Trial Journal of Medical Internet Research |
| title | Real-Time fMRI Neurofeedback Modulation of Dopaminergic Midbrain Activity in Young Adults With Elevated Internet Gaming Disorder Risk: Randomized Controlled Trial |
| title_full | Real-Time fMRI Neurofeedback Modulation of Dopaminergic Midbrain Activity in Young Adults With Elevated Internet Gaming Disorder Risk: Randomized Controlled Trial |
| title_fullStr | Real-Time fMRI Neurofeedback Modulation of Dopaminergic Midbrain Activity in Young Adults With Elevated Internet Gaming Disorder Risk: Randomized Controlled Trial |
| title_full_unstemmed | Real-Time fMRI Neurofeedback Modulation of Dopaminergic Midbrain Activity in Young Adults With Elevated Internet Gaming Disorder Risk: Randomized Controlled Trial |
| title_short | Real-Time fMRI Neurofeedback Modulation of Dopaminergic Midbrain Activity in Young Adults With Elevated Internet Gaming Disorder Risk: Randomized Controlled Trial |
| title_sort | real time fmri neurofeedback modulation of dopaminergic midbrain activity in young adults with elevated internet gaming disorder risk randomized controlled trial |
| url | https://www.jmir.org/2025/1/e64687 |
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