Clinical symptoms and surgical outcome of colloid cysts of the third ventricle: A multicenter retrospective study
Introduction: Colloid cysts of the third ventricle are benign brain lesions that may obstruct cerebrospinal fluid flow within the ventricular system and cause symptoms like headaches, deterioration of vision, and acute hydrocephalus. Research question: What is the clinical outcome of surgical treatm...
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Elsevier
2025-01-01
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| Series: | Brain and Spine |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772529425000153 |
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| author | V.M. Butenschoen N. Lange A. Quiring L. Mikhina J. Gempt M. Shah J. Beck P. Evangelou V. Rohde D. Jankovic F. Ringel I. Janssen K. Schaller C.F. Freyschlag C. Thomé S. Maurer M. Czabanka P. Leissa P. Vajkoczy B. Meyer |
| author_facet | V.M. Butenschoen N. Lange A. Quiring L. Mikhina J. Gempt M. Shah J. Beck P. Evangelou V. Rohde D. Jankovic F. Ringel I. Janssen K. Schaller C.F. Freyschlag C. Thomé S. Maurer M. Czabanka P. Leissa P. Vajkoczy B. Meyer |
| author_sort | V.M. Butenschoen |
| collection | DOAJ |
| description | Introduction: Colloid cysts of the third ventricle are benign brain lesions that may obstruct cerebrospinal fluid flow within the ventricular system and cause symptoms like headaches, deterioration of vision, and acute hydrocephalus. Research question: What is the clinical outcome of surgical treatment of third ventricle colloid cysts, and what factors are influencing long-term complications? Material and methods: In this multicenter retrospective cohort study performed between 2008 and 2023, we assessed the preoperative clinical status, the colloid cyst risk score, surgical techniques, and the clinical outcome of patients undergoing surgical cyst resection for incidental and symptomatic colloid cysts of the third ventricle. We specifically focused on long-term data such as shunt dependency and postoperative complications. Results: In total, 190 patients were included. Most presented with headaches (75,3%), while 25% showed signs of acute and 36% signs of chronic hydrocephalus. In 23% of the patients, short-term memory was impaired. The surgical treatment presented a safe and definite treatment, with wound healing disorders (6.3%) and CSF leakage (4.7%) being the most frequently encountered complications. Only 5.3% showed a postoperative shunt dependency. Discussion and conclusion: The surgical treatment of colloid cysts of the third ventricle represents a safe procedure. Acute hydrocephalus was observed more frequently than previously described, and shunt dependency after surgery was low. (211/250 words) |
| format | Article |
| id | doaj-art-c069fda373154c35a69bd99ce5193725 |
| institution | Kabale University |
| issn | 2772-5294 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brain and Spine |
| spelling | doaj-art-c069fda373154c35a69bd99ce51937252025-02-04T04:10:41ZengElsevierBrain and Spine2772-52942025-01-015104196Clinical symptoms and surgical outcome of colloid cysts of the third ventricle: A multicenter retrospective studyV.M. Butenschoen0N. Lange1A. Quiring2L. Mikhina3J. Gempt4M. Shah5J. Beck6P. Evangelou7V. Rohde8D. Jankovic9F. Ringel10I. Janssen11K. Schaller12C.F. Freyschlag13C. Thomé14S. Maurer15M. Czabanka16P. Leissa17P. Vajkoczy18B. Meyer19Department of Neurosurgery, Technical University Munich, School of Medicine, Germany, Ismaningerstr. 22, 81675, Munich, Germany; Corresponding author. Technical University Munich, School of Medicine, Department of Neurosurgery Klinikum rechts der Isar, Ismaningerstr. 22, Munich, 81675, Germany.Department of Neurosurgery, Technical University Munich, School of Medicine, Germany, Ismaningerstr. 22, 81675, Munich, GermanyDepartment of Neurosurgery, Technical University Munich, School of Medicine, Germany, Ismaningerstr. 22, 81675, Munich, GermanyDepartment of Neurosurgery, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20251, Hamburg, GermanyDepartment of Neurosurgery, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20251, Hamburg, GermanyDepartment of Neurosurgery, Medical Center, University of Freiburg, Freiburg, Breisacher Str. 64, 79106, Freiburg im Breisgau, GermanyDepartment of Neurosurgery, Medical Center, University of Freiburg, Freiburg, Breisacher Str. 64, 79106, Freiburg im Breisgau, GermanyDepartment of Neurosurgery, Georg-August-University Göttingen, Robert-Koch-Strasse 40, 37075, Göttingen, GermanyDepartment of Neurosurgery, Georg-August-University Göttingen, Robert-Koch-Strasse 40, 37075, Göttingen, GermanyDepartment of Neurosurgery, University Medical Center, Johannes Gutenberg University of Mainz, Langenbeckstr. 1, 55131, Mainz, GermanyDepartment of Neurosurgery, University Medical Center, Johannes Gutenberg University of Mainz, Langenbeckstr. 1, 55131, Mainz, GermanyDepartment of Neurosurgery, Geneva University Medical Center & Faculty of Medicine, University of Geneva, Rue Gabrielle-Perret-Gentil 4, 1205, Geneva, SwitzerlandDepartment of Neurosurgery, Geneva University Medical Center & Faculty of Medicine, University of Geneva, Rue Gabrielle-Perret-Gentil 4, 1205, Geneva, SwitzerlandDepartment of Neurosurgery, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, AustriaDepartment of Neurosurgery, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, AustriaDepartment of Neurosurgery, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, GermanyDepartment of Neurosurgery, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, GermanyDepartment of Neurosurgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Augustenburger Platz 1, 13353, Berlin, GermanyDepartment of Neurosurgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Augustenburger Platz 1, 13353, Berlin, GermanyDepartment of Neurosurgery, Technical University Munich, School of Medicine, Germany, Ismaningerstr. 22, 81675, Munich, GermanyIntroduction: Colloid cysts of the third ventricle are benign brain lesions that may obstruct cerebrospinal fluid flow within the ventricular system and cause symptoms like headaches, deterioration of vision, and acute hydrocephalus. Research question: What is the clinical outcome of surgical treatment of third ventricle colloid cysts, and what factors are influencing long-term complications? Material and methods: In this multicenter retrospective cohort study performed between 2008 and 2023, we assessed the preoperative clinical status, the colloid cyst risk score, surgical techniques, and the clinical outcome of patients undergoing surgical cyst resection for incidental and symptomatic colloid cysts of the third ventricle. We specifically focused on long-term data such as shunt dependency and postoperative complications. Results: In total, 190 patients were included. Most presented with headaches (75,3%), while 25% showed signs of acute and 36% signs of chronic hydrocephalus. In 23% of the patients, short-term memory was impaired. The surgical treatment presented a safe and definite treatment, with wound healing disorders (6.3%) and CSF leakage (4.7%) being the most frequently encountered complications. Only 5.3% showed a postoperative shunt dependency. Discussion and conclusion: The surgical treatment of colloid cysts of the third ventricle represents a safe procedure. Acute hydrocephalus was observed more frequently than previously described, and shunt dependency after surgery was low. (211/250 words)http://www.sciencedirect.com/science/article/pii/S2772529425000153Colloid cystIntraventricular surgeryHydrocephalus |
| spellingShingle | V.M. Butenschoen N. Lange A. Quiring L. Mikhina J. Gempt M. Shah J. Beck P. Evangelou V. Rohde D. Jankovic F. Ringel I. Janssen K. Schaller C.F. Freyschlag C. Thomé S. Maurer M. Czabanka P. Leissa P. Vajkoczy B. Meyer Clinical symptoms and surgical outcome of colloid cysts of the third ventricle: A multicenter retrospective study Brain and Spine Colloid cyst Intraventricular surgery Hydrocephalus |
| title | Clinical symptoms and surgical outcome of colloid cysts of the third ventricle: A multicenter retrospective study |
| title_full | Clinical symptoms and surgical outcome of colloid cysts of the third ventricle: A multicenter retrospective study |
| title_fullStr | Clinical symptoms and surgical outcome of colloid cysts of the third ventricle: A multicenter retrospective study |
| title_full_unstemmed | Clinical symptoms and surgical outcome of colloid cysts of the third ventricle: A multicenter retrospective study |
| title_short | Clinical symptoms and surgical outcome of colloid cysts of the third ventricle: A multicenter retrospective study |
| title_sort | clinical symptoms and surgical outcome of colloid cysts of the third ventricle a multicenter retrospective study |
| topic | Colloid cyst Intraventricular surgery Hydrocephalus |
| url | http://www.sciencedirect.com/science/article/pii/S2772529425000153 |
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