Structural insights into MPXV P1 protein and its orthologs reveal conformational dynamics and a conserved antiviral pocket
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
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| Series: | Emerging Microbes and Infections |
| Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2025.2515408 |
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| _version_ | 1849422043198521344 |
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| author | Xincheng Ni Yuanda Wang Xinyu Fan Jiao Yu Jian Lei |
| author_facet | Xincheng Ni Yuanda Wang Xinyu Fan Jiao Yu Jian Lei |
| author_sort | Xincheng Ni |
| collection | DOAJ |
| format | Article |
| id | doaj-art-c0616c2ebdb14dceb9e932d04ca1882a |
| institution | Kabale University |
| issn | 2222-1751 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj-art-c0616c2ebdb14dceb9e932d04ca1882a2025-08-20T03:31:15ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512025-12-0114110.1080/22221751.2025.2515408Structural insights into MPXV P1 protein and its orthologs reveal conformational dynamics and a conserved antiviral pocketXincheng Ni0Yuanda Wang1Xinyu Fan2Jiao Yu3Jian Lei4National Clinical Research Center for Geriatrics, and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaNational Clinical Research Center for Geriatrics, and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaNational Clinical Research Center for Geriatrics, and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaNational Clinical Research Center for Geriatrics, and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaNational Clinical Research Center for Geriatrics, and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, Chinahttps://www.tandfonline.com/doi/10.1080/22221751.2025.2515408 |
| spellingShingle | Xincheng Ni Yuanda Wang Xinyu Fan Jiao Yu Jian Lei Structural insights into MPXV P1 protein and its orthologs reveal conformational dynamics and a conserved antiviral pocket Emerging Microbes and Infections |
| title | Structural insights into MPXV P1 protein and its orthologs reveal conformational dynamics and a conserved antiviral pocket |
| title_full | Structural insights into MPXV P1 protein and its orthologs reveal conformational dynamics and a conserved antiviral pocket |
| title_fullStr | Structural insights into MPXV P1 protein and its orthologs reveal conformational dynamics and a conserved antiviral pocket |
| title_full_unstemmed | Structural insights into MPXV P1 protein and its orthologs reveal conformational dynamics and a conserved antiviral pocket |
| title_short | Structural insights into MPXV P1 protein and its orthologs reveal conformational dynamics and a conserved antiviral pocket |
| title_sort | structural insights into mpxv p1 protein and its orthologs reveal conformational dynamics and a conserved antiviral pocket |
| url | https://www.tandfonline.com/doi/10.1080/22221751.2025.2515408 |
| work_keys_str_mv | AT xinchengni structuralinsightsintompxvp1proteinanditsorthologsrevealconformationaldynamicsandaconservedantiviralpocket AT yuandawang structuralinsightsintompxvp1proteinanditsorthologsrevealconformationaldynamicsandaconservedantiviralpocket AT xinyufan structuralinsightsintompxvp1proteinanditsorthologsrevealconformationaldynamicsandaconservedantiviralpocket AT jiaoyu structuralinsightsintompxvp1proteinanditsorthologsrevealconformationaldynamicsandaconservedantiviralpocket AT jianlei structuralinsightsintompxvp1proteinanditsorthologsrevealconformationaldynamicsandaconservedantiviralpocket |