Lower Respiratory Tract Infection in a Renal Transplant Recipient: Do not Forget Metapneumovirus

Human metapneumovirus (hMPV) is emerging as a cause of a severe respiratory tract infection in immunocompromised patients. hMPV pneumonia has only been seldom reported in nonpulmonary solid organ transplanted patients, such as renal transplant recipients. We report here a case of a 39-year-old patie...

Full description

Saved in:
Bibliographic Details
Main Authors: N. Noel, B. Rammaert, J. Zuber, N. Sayre, M. F. Mamzer-Bruneel, M. Leruez-Ville, L. Mascard, M. Lecuit, O. Lortholary
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Transplantation
Online Access:http://dx.doi.org/10.1155/2012/353871
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849684722784927744
author N. Noel
B. Rammaert
J. Zuber
N. Sayre
M. F. Mamzer-Bruneel
M. Leruez-Ville
L. Mascard
M. Lecuit
O. Lortholary
author_facet N. Noel
B. Rammaert
J. Zuber
N. Sayre
M. F. Mamzer-Bruneel
M. Leruez-Ville
L. Mascard
M. Lecuit
O. Lortholary
author_sort N. Noel
collection DOAJ
description Human metapneumovirus (hMPV) is emerging as a cause of a severe respiratory tract infection in immunocompromised patients. hMPV pneumonia has only been seldom reported in nonpulmonary solid organ transplanted patients, such as renal transplant recipients. We report here a case of a 39-year-old patient presenting with fever, cough, and interstitial opacities on CT scan diagnosed as a nonsevere hMPV pneumonia 11 years after a renal transplantation. Infection resolved spontaneously. Differential diagnosis with Pneumocystis pneumonia was discussed. We review the medical literature and discuss clinical presentation and detection methods that can be proposed in solid organ transplant recipients.
format Article
id doaj-art-c05fd8fd305b4b74a6159b904de92de2
institution DOAJ
issn 2090-6943
2090-6951
language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series Case Reports in Transplantation
spelling doaj-art-c05fd8fd305b4b74a6159b904de92de22025-08-20T03:23:23ZengWileyCase Reports in Transplantation2090-69432090-69512012-01-01201210.1155/2012/353871353871Lower Respiratory Tract Infection in a Renal Transplant Recipient: Do not Forget MetapneumovirusN. Noel0B. Rammaert1J. Zuber2N. Sayre3M. F. Mamzer-Bruneel4M. Leruez-Ville5L. Mascard6M. Lecuit7O. Lortholary8Université Paris Descartes, Sorbonne Paris Cité and Hôpital Necker-Enfants Malades, Service des Maladies Infectieuses et Tropicales, Centre d’Infectiologie Necker-Pasteur, Institut Imagine, AP-HP, 149 rue de Sèvres, 75743 Paris Cedex 15, FranceUniversité Paris Descartes, Sorbonne Paris Cité and Hôpital Necker-Enfants Malades, Service des Maladies Infectieuses et Tropicales, Centre d’Infectiologie Necker-Pasteur, Institut Imagine, AP-HP, 149 rue de Sèvres, 75743 Paris Cedex 15, FranceUniversité Paris Descartes, Sorbonne Paris Cité and Hôpital Necker-Enfants Malades, Service de Transplantation Rénale, AP-HP, 75743 Paris Cedex 15, FranceUniversité Paris Descartes, Sorbonne Paris Cité and Hôpital Necker-Enfants Malades, Service des Maladies Infectieuses et Tropicales, Centre d’Infectiologie Necker-Pasteur, Institut Imagine, AP-HP, 149 rue de Sèvres, 75743 Paris Cedex 15, FranceUniversité Paris Descartes, Sorbonne Paris Cité and Hôpital Necker-Enfants Malades, Service de Transplantation Rénale, AP-HP, 75743 Paris Cedex 15, FranceUniversité Paris Descartes, Sorbonne Paris Cité and Hôpital Necker-Enfants Malades, Laboratoire de Microbiologie, Unité de Virologie, AP-HP, 75743 Paris Cedex 15, FranceUniversité Paris Descartes, Sorbonne Paris Cité and Hôpital Necker-Enfants Malades, Laboratoire de Microbiologie, Unité de Virologie, AP-HP, 75743 Paris Cedex 15, FranceUniversité Paris Descartes, Sorbonne Paris Cité and Hôpital Necker-Enfants Malades, Service des Maladies Infectieuses et Tropicales, Centre d’Infectiologie Necker-Pasteur, Institut Imagine, AP-HP, 149 rue de Sèvres, 75743 Paris Cedex 15, FranceUniversité Paris Descartes, Sorbonne Paris Cité and Hôpital Necker-Enfants Malades, Service des Maladies Infectieuses et Tropicales, Centre d’Infectiologie Necker-Pasteur, Institut Imagine, AP-HP, 149 rue de Sèvres, 75743 Paris Cedex 15, FranceHuman metapneumovirus (hMPV) is emerging as a cause of a severe respiratory tract infection in immunocompromised patients. hMPV pneumonia has only been seldom reported in nonpulmonary solid organ transplanted patients, such as renal transplant recipients. We report here a case of a 39-year-old patient presenting with fever, cough, and interstitial opacities on CT scan diagnosed as a nonsevere hMPV pneumonia 11 years after a renal transplantation. Infection resolved spontaneously. Differential diagnosis with Pneumocystis pneumonia was discussed. We review the medical literature and discuss clinical presentation and detection methods that can be proposed in solid organ transplant recipients.http://dx.doi.org/10.1155/2012/353871
spellingShingle N. Noel
B. Rammaert
J. Zuber
N. Sayre
M. F. Mamzer-Bruneel
M. Leruez-Ville
L. Mascard
M. Lecuit
O. Lortholary
Lower Respiratory Tract Infection in a Renal Transplant Recipient: Do not Forget Metapneumovirus
Case Reports in Transplantation
title Lower Respiratory Tract Infection in a Renal Transplant Recipient: Do not Forget Metapneumovirus
title_full Lower Respiratory Tract Infection in a Renal Transplant Recipient: Do not Forget Metapneumovirus
title_fullStr Lower Respiratory Tract Infection in a Renal Transplant Recipient: Do not Forget Metapneumovirus
title_full_unstemmed Lower Respiratory Tract Infection in a Renal Transplant Recipient: Do not Forget Metapneumovirus
title_short Lower Respiratory Tract Infection in a Renal Transplant Recipient: Do not Forget Metapneumovirus
title_sort lower respiratory tract infection in a renal transplant recipient do not forget metapneumovirus
url http://dx.doi.org/10.1155/2012/353871
work_keys_str_mv AT nnoel lowerrespiratorytractinfectioninarenaltransplantrecipientdonotforgetmetapneumovirus
AT brammaert lowerrespiratorytractinfectioninarenaltransplantrecipientdonotforgetmetapneumovirus
AT jzuber lowerrespiratorytractinfectioninarenaltransplantrecipientdonotforgetmetapneumovirus
AT nsayre lowerrespiratorytractinfectioninarenaltransplantrecipientdonotforgetmetapneumovirus
AT mfmamzerbruneel lowerrespiratorytractinfectioninarenaltransplantrecipientdonotforgetmetapneumovirus
AT mleruezville lowerrespiratorytractinfectioninarenaltransplantrecipientdonotforgetmetapneumovirus
AT lmascard lowerrespiratorytractinfectioninarenaltransplantrecipientdonotforgetmetapneumovirus
AT mlecuit lowerrespiratorytractinfectioninarenaltransplantrecipientdonotforgetmetapneumovirus
AT olortholary lowerrespiratorytractinfectioninarenaltransplantrecipientdonotforgetmetapneumovirus