Clear Aligner Treatment: Indications, Advantages, and Adverse Effects—A Systematic Review

<b>Background/Objectives</b>: Clear aligner treatment (CAT) has gained interest among clinicians as well as among patients. The aim of the present study was to systematically review the literature regarding current viewpoints on indications, contraindications, advantages, disadvantages,...

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Main Authors: Clara Rasborg Hartogsohn, Liselotte Sonnesen
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Dentistry Journal
Subjects:
Online Access:https://www.mdpi.com/2304-6767/13/1/40
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author Clara Rasborg Hartogsohn
Liselotte Sonnesen
author_facet Clara Rasborg Hartogsohn
Liselotte Sonnesen
author_sort Clara Rasborg Hartogsohn
collection DOAJ
description <b>Background/Objectives</b>: Clear aligner treatment (CAT) has gained interest among clinicians as well as among patients. The aim of the present study was to systematically review the literature regarding current viewpoints on indications, contraindications, advantages, disadvantages, and adverse effects in CAT. <b>Methods</b>: A search was performed in the PubMed and Embase databases, yielding 18 studies eligible for inclusion. <b>Results</b>: Current indications for CAT are mild to moderate malocclusions. Severe malocclusions with impactions or severe craniofacial skeletal deviations are contraindications. The advantages were oral hygiene and oral health as the most common, and disadvantages of CAT have been noted by several studies, including CAT still being inferior to fixed appliance treatment (FAT) in all orthodontic movements. Adverse effects were potential health risks due to microplastics and a decrease in condyle bone volume. <b>Conclusions</b>: No firm conclusions can be drawn regarding indications for CAT except for mild to moderate malocclusion. Severe malocclusions with impactions or severe craniofacial skeletal deviations are considered contraindications. In more complex cases, CAT is still considered inferior to FAT, although CAT contains advantages. There are disadvantages in CAT which clinicians should consider when choosing a type of orthodontic appliance for treating specific malocclusions. Only a few adverse effects in CAT were presented by the included studies. More high-quality research is needed regarding indications and contraindications for CAT.
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spelling doaj-art-c05e88d6a345467392715387ec878bdf2025-01-24T13:28:43ZengMDPI AGDentistry Journal2304-67672025-01-011314010.3390/dj13010040Clear Aligner Treatment: Indications, Advantages, and Adverse Effects—A Systematic ReviewClara Rasborg Hartogsohn0Liselotte Sonnesen1Section of Orthodontics, Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, DenmarkSection of Orthodontics, Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark<b>Background/Objectives</b>: Clear aligner treatment (CAT) has gained interest among clinicians as well as among patients. The aim of the present study was to systematically review the literature regarding current viewpoints on indications, contraindications, advantages, disadvantages, and adverse effects in CAT. <b>Methods</b>: A search was performed in the PubMed and Embase databases, yielding 18 studies eligible for inclusion. <b>Results</b>: Current indications for CAT are mild to moderate malocclusions. Severe malocclusions with impactions or severe craniofacial skeletal deviations are contraindications. The advantages were oral hygiene and oral health as the most common, and disadvantages of CAT have been noted by several studies, including CAT still being inferior to fixed appliance treatment (FAT) in all orthodontic movements. Adverse effects were potential health risks due to microplastics and a decrease in condyle bone volume. <b>Conclusions</b>: No firm conclusions can be drawn regarding indications for CAT except for mild to moderate malocclusion. Severe malocclusions with impactions or severe craniofacial skeletal deviations are considered contraindications. In more complex cases, CAT is still considered inferior to FAT, although CAT contains advantages. There are disadvantages in CAT which clinicians should consider when choosing a type of orthodontic appliance for treating specific malocclusions. Only a few adverse effects in CAT were presented by the included studies. More high-quality research is needed regarding indications and contraindications for CAT.https://www.mdpi.com/2304-6767/13/1/40orthodonticsclear aligner treatmentmalocclusions
spellingShingle Clara Rasborg Hartogsohn
Liselotte Sonnesen
Clear Aligner Treatment: Indications, Advantages, and Adverse Effects—A Systematic Review
Dentistry Journal
orthodontics
clear aligner treatment
malocclusions
title Clear Aligner Treatment: Indications, Advantages, and Adverse Effects—A Systematic Review
title_full Clear Aligner Treatment: Indications, Advantages, and Adverse Effects—A Systematic Review
title_fullStr Clear Aligner Treatment: Indications, Advantages, and Adverse Effects—A Systematic Review
title_full_unstemmed Clear Aligner Treatment: Indications, Advantages, and Adverse Effects—A Systematic Review
title_short Clear Aligner Treatment: Indications, Advantages, and Adverse Effects—A Systematic Review
title_sort clear aligner treatment indications advantages and adverse effects a systematic review
topic orthodontics
clear aligner treatment
malocclusions
url https://www.mdpi.com/2304-6767/13/1/40
work_keys_str_mv AT clararasborghartogsohn clearalignertreatmentindicationsadvantagesandadverseeffectsasystematicreview
AT liselottesonnesen clearalignertreatmentindicationsadvantagesandadverseeffectsasystematicreview