Development and validation of a nomogram for predicting calcification of arteriovenous access in hemodialysis patients
Background In patients with end-stage renal disease (ESRD), vascular calcification significantly impairs hemodialysis (HD) vascular access functionality, compromising both dialysis efficacy and long-term patency. Early risk prediction of vascular calcification facilitates timely clinical interventio...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
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| Series: | Renal Failure |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/0886022X.2025.2542980 |
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| _version_ | 1849405620645527552 |
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| author | Xueying Li Xiaocui Wang Bonan Yan Yuanke Zhou Ling Li Xiaopeng Huang Qiqi Wang Enjie Tang |
| author_facet | Xueying Li Xiaocui Wang Bonan Yan Yuanke Zhou Ling Li Xiaopeng Huang Qiqi Wang Enjie Tang |
| author_sort | Xueying Li |
| collection | DOAJ |
| description | Background In patients with end-stage renal disease (ESRD), vascular calcification significantly impairs hemodialysis (HD) vascular access functionality, compromising both dialysis efficacy and long-term patency. Early risk prediction of vascular calcification facilitates timely clinical interventions to preserve vascular access integrity.Methods A cross-sectional analysis was performed. Risk factors for vascular calcification in CKD patients were identified from the literature and Kidney Disease: Improving Global Outcomes guidelines. All variable selection and model training procedures were conducted on the training set. Univariate logistic regression was performed for all candidate variables. A nomogram was then constructed based on the final multivariate logistic model to facilitate clinical interpretation.Result A total of 136 HD patients were included. The predictive model, relying on arteriovenous (AV) access usage time, hip circumference, and diabetes status, is reliable and clinically actionable tool for predicting AV access calcification. Its robust performance across validation and subgroup analyses supports its potential for integration into routine clinical practice.Conclusion This study developed a nomogram-based predictive model for calcification, providing a simple, cost-effective, and reliable tool for early risk assessment. Monitoring hip circumference may serve as a practical approach for identifying high-risk patients, allowing for timely intervention and improved vascular access outcomes. |
| format | Article |
| id | doaj-art-c04a3ad4bf3f40d48b674f0c2b34b429 |
| institution | Kabale University |
| issn | 0886-022X 1525-6049 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Renal Failure |
| spelling | doaj-art-c04a3ad4bf3f40d48b674f0c2b34b4292025-08-20T03:36:37ZengTaylor & Francis GroupRenal Failure0886-022X1525-60492025-12-0147110.1080/0886022X.2025.2542980Development and validation of a nomogram for predicting calcification of arteriovenous access in hemodialysis patientsXueying Li0Xiaocui Wang1Bonan Yan2Yuanke Zhou3Ling Li4Xiaopeng Huang5Qiqi Wang6Enjie Tang7Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China925 Hospital of PLA Joint Logistics Support Force, Guizhou, ChinaHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China925 Hospital of PLA Joint Logistics Support Force, Guizhou, ChinaBackground In patients with end-stage renal disease (ESRD), vascular calcification significantly impairs hemodialysis (HD) vascular access functionality, compromising both dialysis efficacy and long-term patency. Early risk prediction of vascular calcification facilitates timely clinical interventions to preserve vascular access integrity.Methods A cross-sectional analysis was performed. Risk factors for vascular calcification in CKD patients were identified from the literature and Kidney Disease: Improving Global Outcomes guidelines. All variable selection and model training procedures were conducted on the training set. Univariate logistic regression was performed for all candidate variables. A nomogram was then constructed based on the final multivariate logistic model to facilitate clinical interpretation.Result A total of 136 HD patients were included. The predictive model, relying on arteriovenous (AV) access usage time, hip circumference, and diabetes status, is reliable and clinically actionable tool for predicting AV access calcification. Its robust performance across validation and subgroup analyses supports its potential for integration into routine clinical practice.Conclusion This study developed a nomogram-based predictive model for calcification, providing a simple, cost-effective, and reliable tool for early risk assessment. Monitoring hip circumference may serve as a practical approach for identifying high-risk patients, allowing for timely intervention and improved vascular access outcomes.https://www.tandfonline.com/doi/10.1080/0886022X.2025.2542980Arteriovenous accesshemodialysiscalcificationhip circumference |
| spellingShingle | Xueying Li Xiaocui Wang Bonan Yan Yuanke Zhou Ling Li Xiaopeng Huang Qiqi Wang Enjie Tang Development and validation of a nomogram for predicting calcification of arteriovenous access in hemodialysis patients Renal Failure Arteriovenous access hemodialysis calcification hip circumference |
| title | Development and validation of a nomogram for predicting calcification of arteriovenous access in hemodialysis patients |
| title_full | Development and validation of a nomogram for predicting calcification of arteriovenous access in hemodialysis patients |
| title_fullStr | Development and validation of a nomogram for predicting calcification of arteriovenous access in hemodialysis patients |
| title_full_unstemmed | Development and validation of a nomogram for predicting calcification of arteriovenous access in hemodialysis patients |
| title_short | Development and validation of a nomogram for predicting calcification of arteriovenous access in hemodialysis patients |
| title_sort | development and validation of a nomogram for predicting calcification of arteriovenous access in hemodialysis patients |
| topic | Arteriovenous access hemodialysis calcification hip circumference |
| url | https://www.tandfonline.com/doi/10.1080/0886022X.2025.2542980 |
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