Methylated ARHGAP40 DNA as a potential biomarker for early diagnosis in high-grade ovarian serous cancer

Methylated ARHGAP40 DNA as a potential biomarker for early diagnosis in high-grade ovarian serous cancer

Abstract Ovarian cancer ranks as the eighth most common malignancy in women globally. Early detection remains a critical challenge for improving ovarian cancer diagnosis and treatment outcomes. Our prior study demonstrated that ARHGAP40 downregulation in basal cell carcinoma is attributed to CpG isl...

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Bibliographic Details
Main Authors: Jiaxin Chai, Dongni Leng, Shuwei Guo, Rusong Zhang, Jiandong Wang, Yun Gu, Qiu Rao
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
ARHGAP40
Methylation, CfDNA
CtDNA
Online Access:https://doi.org/10.1186/s13048-025-01729-9
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