Hand hygiene for prevention and control of viral infections: the role of Amuchina Gel Xgerm [Accepted for publication]
Introduction: Alcohol-based hand sanitizers are used in healthcare settings, but their efficacy against both enveloped and non-enveloped viruses requires further investigation. Methods: In this study, viral suspensions composed by the test virus, an interfering substance, and the test product, we...
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2024-12-01
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| Online Access: | https://journals.aboutscience.eu/index.php/aboutopen/article/view/3435 |
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| author | Claudio Cermelli Elisabetta Blasi Alessandra Capezzone de Joannon Maria Ilaria Roselli Daniele Frollano Michela Procaccini |
| author_facet | Claudio Cermelli Elisabetta Blasi Alessandra Capezzone de Joannon Maria Ilaria Roselli Daniele Frollano Michela Procaccini |
| author_sort | Claudio Cermelli |
| collection | DOAJ |
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Introduction: Alcohol-based hand sanitizers are used in healthcare settings, but their efficacy against both enveloped and non-enveloped viruses requires further investigation.
Methods: In this study, viral suspensions composed by the test virus, an interfering substance, and the test product, were exposed to Amuchina Gel Xgerm (100 g of the product contains 74 g of ethanol 96%; Angelini Pharma S.p.A) at 80% dilution in water, according to the European Standard EN14476:2013+A2:2019 –quantitative suspension test for the evaluation of virucidal activity in the medical area– for chemical disinfectants and antiseptics, in the presence of bovine serum albumin 0.3 g/L. The residual viral titers were measured.
Results: Sixty second exposures to the product determined a ≥4 log10 reduction of virus titer in all cases. For adenovirus type 5, human coxsakievirus, herpesvirus 1 and influenza virus A H1N1, a ≥4 log10 reduction of virus titer was obtained already after 30 s. Amuchina Gel Xgerm demonstrated effectiveness against seven virus families, including both enveloped and non-enveloped viruses.
Conclusion: Amuchina Gel Xgerm is a preventive measure against infection spread in healthcare and community settings, contributing to improved healthcare management.
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| format | Article |
| id | doaj-art-c03fc41ce0fb458d90ce8dbee7880194 |
| institution | DOAJ |
| issn | 2465-2628 |
| language | English |
| publishDate | 2024-12-01 |
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| spelling | doaj-art-c03fc41ce0fb458d90ce8dbee78801942025-08-20T03:00:53ZengAboutScience SrlAboutOpen2465-26282024-12-0111110.33393/ao.2024.3435Hand hygiene for prevention and control of viral infections: the role of Amuchina Gel Xgerm [Accepted for publication]Claudio Cermelli0Elisabetta Blasi1Alessandra Capezzone de Joannon2Maria Ilaria Roselli3Daniele Frollano4Michela Procaccini5Department of Surgical, Medical, Dental and Morphological Sciences with Interest in Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena - ItalyDepartment of Surgical, Medical, Dental and Morphological Sciences with Interest in Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena - ItalyGlobal R&D Angelini Pharma S.p.A, Ancona - ItalyAngelini Pharma S.p.A, Rome - ItalyAngelini Pharma S.p.A, Rome - ItalyAngelini Pharma S.p.A, Rome - Italy Introduction: Alcohol-based hand sanitizers are used in healthcare settings, but their efficacy against both enveloped and non-enveloped viruses requires further investigation. Methods: In this study, viral suspensions composed by the test virus, an interfering substance, and the test product, were exposed to Amuchina Gel Xgerm (100 g of the product contains 74 g of ethanol 96%; Angelini Pharma S.p.A) at 80% dilution in water, according to the European Standard EN14476:2013+A2:2019 –quantitative suspension test for the evaluation of virucidal activity in the medical area– for chemical disinfectants and antiseptics, in the presence of bovine serum albumin 0.3 g/L. The residual viral titers were measured. Results: Sixty second exposures to the product determined a ≥4 log10 reduction of virus titer in all cases. For adenovirus type 5, human coxsakievirus, herpesvirus 1 and influenza virus A H1N1, a ≥4 log10 reduction of virus titer was obtained already after 30 s. Amuchina Gel Xgerm demonstrated effectiveness against seven virus families, including both enveloped and non-enveloped viruses. Conclusion: Amuchina Gel Xgerm is a preventive measure against infection spread in healthcare and community settings, contributing to improved healthcare management. https://journals.aboutscience.eu/index.php/aboutopen/article/view/3435Alcohol-based hand sanitizer Enveloped virusInfection preventionNon-enveloped virus |
| spellingShingle | Claudio Cermelli Elisabetta Blasi Alessandra Capezzone de Joannon Maria Ilaria Roselli Daniele Frollano Michela Procaccini Hand hygiene for prevention and control of viral infections: the role of Amuchina Gel Xgerm [Accepted for publication] AboutOpen Alcohol-based hand sanitizer Enveloped virus Infection prevention Non-enveloped virus |
| title | Hand hygiene for prevention and control of viral infections: the role of Amuchina Gel Xgerm [Accepted for publication] |
| title_full | Hand hygiene for prevention and control of viral infections: the role of Amuchina Gel Xgerm [Accepted for publication] |
| title_fullStr | Hand hygiene for prevention and control of viral infections: the role of Amuchina Gel Xgerm [Accepted for publication] |
| title_full_unstemmed | Hand hygiene for prevention and control of viral infections: the role of Amuchina Gel Xgerm [Accepted for publication] |
| title_short | Hand hygiene for prevention and control of viral infections: the role of Amuchina Gel Xgerm [Accepted for publication] |
| title_sort | hand hygiene for prevention and control of viral infections the role of amuchina gel xgerm accepted for publication |
| topic | Alcohol-based hand sanitizer Enveloped virus Infection prevention Non-enveloped virus |
| url | https://journals.aboutscience.eu/index.php/aboutopen/article/view/3435 |
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